Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 IL-17A 100
ng/mL
 3
IL-5
 8.0 67
RA2159 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
IL-5
 9.5 72
RA2159 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL-5
 11.5 56
RA2159 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL-5
 10.0 54
RA2159 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL-5
 10.0 63
RA2159 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
IL-5
 10.0 80
N2586 IL-17A 100
ng/mL
 3
IL-5
 11.0 73
N2586 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
IL-5
 11.0 74
N2586 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL-5
 11.0 73
N2586 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL-5
 10.0 73
N2586 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL-5
 12.0 53
N2586 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
IL-5
 8.0 45
RA2159 IL-6 100
ug/mL
 3
IL-5
 10.5 76
RA2159 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
IL-5
 12.0 81
RA2159 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
IL-5
 11.0 64
RA2159 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
IL-5
 11.0 63
RA2159 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
IL-5
 9.0 71
RA2159 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
IL-5
 12.0 62
RA2159 Sigma A6730 3.0
uM
 3
IL-5
 9.0 75
N2586 IL-6 100
ug/mL
 3
IL-5
 10.0 59
N2586 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
IL-5
 11.0 69
N2586 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
IL-5
 8.0 51
N2586 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
IL-5
 10.5 76
N2586 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
IL-5
 11.0 77
N2586 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
IL-5
 11.0 70