Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 4
IL2-Ra
 13.0 66
N2586 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 4
IL2-Ra
 12.0 67
N2586 Tofacitinib 0.3
uM
 4
IL2-Ra
 14.0 47
RA2159 IL-6 100
ug/mL
 4
IL2-Ra
 20.0 71
RA2159 EO1428 1.0
uM
 IL-6 100
ug/mL
 4
IL2-Ra
 12.0 75
RA2159 PI103 0.1
uM
 IL-6 100
ug/mL
 4
IL2-Ra
 11.0 49
RA2159 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 4
IL2-Ra
 14.0 57
RA2159 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 4
IL2-Ra
 13.0 53
RA2159 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 4
IL2-Ra
 13.5 48
RA2159 Ruxolitinib 0.3
uM
 4
IL2-Ra
 13.0 61
N2586 IL-6 100
ug/mL
 4
IL2-Ra
 15.0 53
N2586 EO1428 1.0
uM
 IL-6 100
ug/mL
 4
IL2-Ra
 15.0 50
N2586 PI103 0.1
uM
 IL-6 100
ug/mL
 4
IL2-Ra
 10.0 39
N2586 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 4
IL2-Ra
 12.0 55
N2586 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 4
IL2-Ra
 11.0 63
N2586 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 4
IL2-Ra
 12.0 33
N2586 Ruxolitinib 0.3
uM
 4
IL2-Ra
 12.0 51
RA2159 IL-1 alpha 100
ng/mL
 4
IL2-Ra
 18.0 74
RA2159 EO1428 1.0
uM
 IL-1 alpha 100
ng/mL
 4
IL2-Ra
 17.5 62
RA2159 PI103 0.1
uM
 IL-1 alpha 100
ng/mL
 4
IL2-Ra
 25.0 76
RA2159 Sigma A6730 3.0
uM
 IL-1 alpha 100
ng/mL
 4
IL2-Ra
 15.0 67
RA2159 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 4
IL2-Ra
 15.5 62
RA2159 JNK-IN-11 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL2-Ra
 19.0 54
RA2159 Lestaurtinib 0.3
uM
 4
IL2-Ra
 15.0 64
N2586 IL-1 alpha 100
ng/mL
 4
IL2-Ra
 18.0 55