Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 3
IL-17
 47.0 59
N2586 PD184352 0.1
uM
 3
IL-17
 44.0 83
N2586 Lestaurtinib 0.3
uM
 3
IL-17
 43.0 71
N2586 Ruxolitinib 0.3
uM
 3
IL-17
 48.0 93
N2586 Tofacitinib 0.3
uM
 3
IL-17
 39.0 69
N2586 IKK16 2.0
uM
 3
IL-17
 49.0 56
N2586 JNK-IN-8 3.0
uM
 3
IL-17
 48.0 61
RA2159 IL-17A 100
ng/mL
 3
IL-17
 5904.0 65
RA2159 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
IL-17
 6847.5 64
RA2159 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL-17
 5725.0 74
RA2159 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL-17
 6241.5 70
RA2159 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL-17
 7132.5 56
RA2159 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
IL-17
 6163.0 57
N2586 IL-17A 100
ng/mL
 3
IL-17
 2724.0 72
N2586 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
IL-17
 3962.0 74
N2586 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL-17
 2107.0 60
N2586 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL-17
 3439.5 56
N2586 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
IL-17
 3619.0 61
N2586 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
IL-17
 3204.0 55
RA2159 IL-6 100
ug/mL
 3
IL-17
 52.0 62
RA2159 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
IL-17
 49.0 77
RA2159 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
IL-17
 47.0 52
RA2159 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
IL-17
 51.0 66
RA2159 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
IL-17
 48.0 70
RA2159 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
IL-17
 47.0 79