Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA2159 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | IL-8 | 924.0 | 85 | |
| RA2159 | IKK16 | 2.0 | uM | IGF-I | 100 | ug/mL | 3 | IL-8 | 214.5 | 70 | |
| RA2159 | 3 | IL-8 | 653.0 | 69 | |||||||
| N2586 | IGF-I | 100 | ug/mL | 3 | IL-8 | 1527.0 | 73 | ||||
| N2586 | PD184352 | 0.1 | uM | IGF-I | 100 | ug/mL | 3 | IL-8 | 676.0 | 88 | |
| N2586 | Lestaurtinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | IL-8 | 795.0 | 86 | |
| N2586 | Ruxolitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | IL-8 | 1506.0 | 90 | |
| N2586 | Tofacitinib | 0.3 | uM | IGF-I | 100 | ug/mL | 3 | IL-8 | 843.0 | 80 | |
| N2586 | IKK16 | 2.0 | uM | IGF-I | 100 | ug/mL | 3 | IL-8 | 656.0 | 85 | |
| N2586 | 3 | IL-8 | 1458.0 | 90 | |||||||
| RA2159 | EGF | 100 | ng/mL | 3 | IL-8 | 708.5 | 76 | ||||
| RA2159 | PD184352 | 0.1 | uM | EGF | 100 | ng/mL | 3 | IL-8 | 693.0 | 54 | |
| RA2159 | Lestaurtinib | 0.3 | uM | EGF | 100 | ng/mL | 3 | IL-8 | 781.0 | 73 | |
| RA2159 | Ruxolitinib | 0.3 | uM | EGF | 100 | ng/mL | 3 | IL-8 | 1380.5 | 46 | |
| RA2159 | Tofacitinib | 0.3 | uM | EGF | 100 | ng/mL | 3 | IL-8 | 614.0 | 74 | |
| RA2159 | IKK16 | 2.0 | uM | EGF | 100 | ng/mL | 3 | IL-8 | 377.5 | 58 | |
| RA2159 | JNK-IN-11 | 0.3 | uM | 3 | IL-8 | 548.0 | 85 | ||||
| N2586 | EGF | 100 | ng/mL | 3 | IL-8 | 2634.0 | 81 | ||||
| N2586 | PD184352 | 0.1 | uM | EGF | 100 | ng/mL | 3 | IL-8 | 1436.0 | 83 | |
| N2586 | Lestaurtinib | 0.3 | uM | EGF | 100 | ng/mL | 3 | IL-8 | 1333.0 | 63 | |
| N2586 | Ruxolitinib | 0.3 | uM | EGF | 100 | ng/mL | 3 | IL-8 | 2203.0 | 63 | |
| N2586 | Tofacitinib | 0.3 | uM | EGF | 100 | ng/mL | 3 | IL-8 | 943.0 | 75 | |
| N2586 | IKK16 | 2.0 | uM | EGF | 100 | ng/mL | 3 | IL-8 | 228.0 | 63 | |
| N2586 | JNK-IN-11 | 0.3 | uM | 3 | IL-8 | 232.0 | 50 | ||||
| RA2159 | 3 | IL-8 | 449.0 | 71 |