Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2586 | Lestaurtinib | 0.3 | uM | Visfatin | 1 | ng/mL | 3 | IP-10 | 11.0 | 85 | |
| N2586 | Ruxolitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 3 | IP-10 | 9.5 | 52 | |
| N2586 | Tofacitinib | 0.3 | uM | Visfatin | 1 | ng/mL | 3 | IP-10 | 11.0 | 74 | |
| N2586 | IKK16 | 2.0 | uM | Visfatin | 1 | ng/mL | 3 | IP-10 | 12.0 | 73 | |
| RA2159 | Leptin | 1 | ng/mL | 3 | IP-10 | 14.0 | 90 | ||||
| RA2159 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 3 | IP-10 | 11.0 | 71 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IP-10 | 11.0 | 79 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IP-10 | 8.0 | 78 | |
| RA2159 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IP-10 | 15.5 | 78 | |
| RA2159 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 3 | IP-10 | 11.0 | 76 | |
| N2586 | Leptin | 1 | ng/mL | 3 | IP-10 | 12.0 | 88 | ||||
| N2586 | PD184352 | 0.1 | uM | Leptin | 1 | ng/mL | 3 | IP-10 | 12.0 | 73 | |
| N2586 | Lestaurtinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IP-10 | 12.0 | 81 | |
| N2586 | Ruxolitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IP-10 | 11.0 | 94 | |
| N2586 | Tofacitinib | 0.3 | uM | Leptin | 1 | ng/mL | 3 | IP-10 | 11.0 | 72 | |
| N2586 | IKK16 | 2.0 | uM | Leptin | 1 | ng/mL | 3 | IP-10 | 11.0 | 66 | |
| RA2159 | Adiponectin | 5 | ng/mL | 3 | IP-10 | 11.0 | 74 | ||||
| RA2159 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 3 | IP-10 | 11.0 | 79 | |
| RA2159 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IP-10 | 10.0 | 96 | |
| RA2159 | Ruxolitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IP-10 | 14.0 | 70 | |
| RA2159 | Tofacitinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IP-10 | 12.0 | 79 | |
| RA2159 | IKK16 | 2.0 | uM | Adiponectin | 5 | ng/mL | 3 | IP-10 | 11.0 | 93 | |
| N2586 | Adiponectin | 5 | ng/mL | 3 | IP-10 | 10.0 | 87 | ||||
| N2586 | PD184352 | 0.1 | uM | Adiponectin | 5 | ng/mL | 3 | IP-10 | 12.0 | 72 | |
| N2586 | Lestaurtinib | 0.3 | uM | Adiponectin | 5 | ng/mL | 3 | IP-10 | 13.0 | 73 |