Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 4
TNF-a
 21.0 54
RA2159 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 4
TNF-a
 20.0 62
RA2159 Ruxolitinib 0.3
uM
 4
TNF-a
 14.5 34
N2586 IL-6 100
ug/mL
 4
TNF-a
 18.0 43
N2586 EO1428 1.0
uM
 IL-6 100
ug/mL
 4
TNF-a
 24.0 71
N2586 PI103 0.1
uM
 IL-6 100
ug/mL
 4
TNF-a
 20.0 85
N2586 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 4
TNF-a
 27.0 51
N2586 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 4
TNF-a
 24.0 63
N2586 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 4
TNF-a
 17.0 79
N2586 Ruxolitinib 0.3
uM
 4
TNF-a
 18.0 69
RA2159 IL-1 alpha 100
ng/mL
 4
TNF-a
 35.0 58
RA2159 EO1428 1.0
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 31.0 61
RA2159 PI103 0.1
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 37.0 57
RA2159 Sigma A6730 3.0
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 37.0 71
RA2159 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 36.5 40
RA2159 JNK-IN-11 0.3
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 39.0 54
RA2159 Lestaurtinib 0.3
uM
 4
TNF-a
 18.0 69
N2586 IL-1 alpha 100
ng/mL
 4
TNF-a
 40.0 77
N2586 EO1428 1.0
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 37.0 57
N2586 PI103 0.1
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 31.0 57
N2586 Sigma A6730 3.0
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 38.0 51
N2586 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 21.0 48
N2586 JNK-IN-11 0.3
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 14.0 75
N2586 Lestaurtinib 0.3
uM
 4
TNF-a
 20.5 42
0
TNF-a
 16.0 50