Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 1
CTACK
 21.5 42
N2586 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 1
CTACK
 19.0 42
N2586 IKK16 2.0
uM
 IL-17A 100
ng/mL
 1
CTACK
 18.0 56
RA2159 1
CTACK
 19.0 33
RA2159 PD184352 0.1
uM
 1
CTACK
 29.0 82
RA2159 Lestaurtinib 0.3
uM
 1
CTACK
 20.0 63
RA2159 Ruxolitinib 0.3
uM
 1
CTACK
 14.0 89
RA2159 Tofacitinib 0.3
uM
 1
CTACK
 18.0 63
RA2159 IKK16 2.0
uM
 1
CTACK
 19.0 77
RA2159 JNK-IN-8 3.0
uM
 1
CTACK
 16.0 52
N2586 1
CTACK
 20.0 57
N2586 PD184352 0.1
uM
 1
CTACK
 17.0 65
N2586 Lestaurtinib 0.3
uM
 1
CTACK
 21.0 49
N2586 Ruxolitinib 0.3
uM
 1
CTACK
 18.0 58
N2586 Tofacitinib 0.3
uM
 1
CTACK
 18.0 73
N2586 IKK16 2.0
uM
 1
CTACK
 17.5 60
N2586 JNK-IN-8 3.0
uM
 1
CTACK
 18.0 47
RA2159 EGF 100
ng/mL
 1
CTACK
 23.0 70
RA2159 PD184352 0.1
uM
 EGF 100
ng/mL
 1
CTACK
 17.0 55
RA2159 Lestaurtinib 0.3
uM
 EGF 100
ng/mL
 1
CTACK
 18.0 64
RA2159 Ruxolitinib 0.3
uM
 EGF 100
ng/mL
 1
CTACK
 16.0 63
RA2159 Tofacitinib 0.3
uM
 EGF 100
ng/mL
 1
CTACK
 24.0 62
RA2159 IKK16 2.0
uM
 EGF 100
ng/mL
 1
CTACK
 16.0 62
RA2159 JNK-IN-11 0.3
uM
 1
CTACK
 17.5 62
N2586 EGF 100
ng/mL
 1
CTACK
 16.0 67