Crizotinib KINOMEscan-2 - Dataset (ID:20200)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Protein | Kd | Conc unit |
|---|---|---|---|
| Crizotinib | MET(M1250T) | 0.6 | nM |
| Crizotinib | MET(Y1235D) | 1.5 | nM |
| Crizotinib | MET | 2.1 | nM |
| Crizotinib | ALK | 3.3 | nM |
| Crizotinib | MERTK | 3.6 | nM |
| Crizotinib | ROS1 | 4.1 | nM |
| Crizotinib | EPHB6 | 6.0 | nM |
| Crizotinib | AXL | 7.8 | nM |
| Crizotinib | ABL1(T315I)-phosphorylated | 10.0 | nM |
| Crizotinib | ABL1(T315I)-nonphosphorylated | 12.0 | nM |
| Crizotinib | LTK | 12.0 | nM |
| Crizotinib | SLK | 18.0 | nM |
| Crizotinib | MST1R | 25.0 | nM |
| Crizotinib | LCK | 30.0 | nM |
| Crizotinib | IRAK3 | 31.0 | nM |
| Crizotinib | ABL1(H396P)-nonphosphorylated | 33.0 | nM |
| Crizotinib | TRKB | 37.0 | nM |
| Crizotinib | M4K1 | 39.0 | nM |
| Crizotinib | LOK | 44.0 | nM |
| Crizotinib | IRAK1 | 49.0 | nM |
| Crizotinib | PLK4 | 60.0 | nM |
| Crizotinib | EPHA6 | 65.0 | nM |
| Crizotinib | M3K2 | 72.0 | nM |
| Crizotinib | ABL1(Y253F)-phosphorylated | 74.0 | nM |
| Crizotinib | M4K3 | 75.0 | nM |