SKI-606 KINOMEscan - Dataset - HMS LINCS Database

SKI-606 KINOMEscan - Dataset (ID:20184)

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Small molecules	Proteins

Small Molecule	Protein	Kd	Conc unit
Bosutinib	ABL1(E255K)-phosphorylated	0.05	nM
Bosutinib	ABL1(F317I)-nonphosphorylated	0.63	nM
Bosutinib	ABL1(F317I)-phosphorylated	0.18	nM
Bosutinib	ABL1(F317L)-nonphosphorylated	0.11	nM
Bosutinib	ABL1(F317L)-phosphorylated	0.03	nM
Bosutinib	ABL1(H396P)-nonphosphorylated	0.06	nM
Bosutinib	ABL1(H396P)-phosphorylated	0.06	nM
Bosutinib	ABL1(M351T)-phosphorylated	0.04	nM
Bosutinib	ABL1(Q252H)-nonphosphorylated	0.09	nM
Bosutinib	ABL1(Q252H)-phosphorylated	0.04	nM
Bosutinib	ABL1(T315I)-nonphosphorylated	21.00	nM
Bosutinib	ABL1(T315I)-phosphorylated	3.60	nM
Bosutinib	ABL1(Y253F)-phosphorylated	0.04	nM
Bosutinib	ABL1-nonphosphorylated	0.12	nM
Bosutinib	ABL1-phosphorylated	0.06	nM
Bosutinib	ABL2	1.50	nM
Bosutinib	ACVR1		nM
Bosutinib	ACVR1B		nM
Bosutinib	ACVR2A		nM
Bosutinib	ACVR2B		nM
Bosutinib	ACVRL1		nM
Bosutinib	ADCK3		nM
Bosutinib	ADCK4		nM
Bosutinib	AKT1		nM
Bosutinib	AAK1	2300.00	nM