AZD-1152HQPA KINOMEscan-2 - Dataset (ID:20158)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Protein | Kd | Conc unit |
|---|---|---|---|
| Barasertib | MP2K5 | 2.8 | nM |
| Barasertib | FLT3(K663Q) | 3.9 | nM |
| Barasertib | AURKC | 4.4 | nM |
| Barasertib | AURKB | 4.6 | nM |
| Barasertib | KIT(V559D,T670I) | 7.9 | nM |
| Barasertib | FLT3 | 8.2 | nM |
| Barasertib | KIT(V559D) | 15.0 | nM |
| Barasertib | KIT | 17.0 | nM |
| Barasertib | KIT(L576P) | 34.0 | nM |
| Barasertib | PGFRA | 38.0 | nM |
| Barasertib | PGFRB | 41.0 | nM |
| Barasertib | FLT3(N841I) | 43.0 | nM |
| Barasertib | EPHB6 | 50.0 | nM |
| Barasertib | RET | 80.0 | nM |
| Barasertib | HIPK4 | 97.0 | nM |
| Barasertib | VGFR1 | 110.0 | nM |
| Barasertib | EGFR(G719C) | 120.0 | nM |
| Barasertib | RET(M918T) | 120.0 | nM |
| Barasertib | FLT3(R834Q) | 130.0 | nM |
| Barasertib | RET(V804L) | 140.0 | nM |
| Barasertib | FLT3(ITD) | 140.0 | nM |
| Barasertib | MAP4K5 | 160.0 | nM |
| Barasertib | EGFR(G719S) | 170.0 | nM |
| Barasertib | FLT3(D835H) | 210.0 | nM |
| Barasertib | RET(V804M) | 240.0 | nM |