Lapatinib KINOMEscan-2 - Dataset (ID:20155)
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| Small Molecule | Protein | Kd | Conc unit |
|---|---|---|---|
| Lapatinib | EGFR(G719C) | 0.9 | nM |
| Lapatinib | EGFR(L861Q) | 1.2 | nM |
| Lapatinib | EGFR(G719S) | 2.1 | nM |
| Lapatinib | EGFR(L747-E749del, A750P) | 2.2 | nM |
| Lapatinib | EGFR | 2.4 | nM |
| Lapatinib | EGFR(L858R) | 2.8 | nM |
| Lapatinib | EGFR(L747-T751del,Sins) | 3.5 | nM |
| Lapatinib | EGFR(L747-S752del, P753S) | 3.9 | nM |
| Lapatinib | EGFR(S752-I759del) | 4.2 | nM |
| Lapatinib | ERBB2 | 7.0 | nM |
| Lapatinib | EGFR(E746-A750del) | 8.6 | nM |
| Lapatinib | ERBB4 | 54.0 | nM |
| Lapatinib | PIK3C2B | 670.0 | nM |
| Lapatinib | EGFR(T790M) | 860.0 | nM |
| Lapatinib | PIK4CB | 940.0 | nM |
| Lapatinib | MP2K5 | 1100.0 | nM |
| Lapatinib | SLK | 3300.0 | nM |
| Lapatinib | RIPK2 | 3600.0 | nM |
| Lapatinib | MP2K7 | 4400.0 | nM |
| Lapatinib | LOK | 4400.0 | nM |
| Lapatinib | ERBB3 | 5500.0 | nM |
| Lapatinib | PIK3C2G | 7500.0 | nM |
| Lapatinib | ABL1-nonphosphorylated | nM | |
| Lapatinib | ABL1(Y253F)-phosphorylated | nM | |
| Lapatinib | ABL1(H396P)-nonphosphorylated | nM |