NVP-BHG712 KiNativ -- multiple dose experiment - Dataset (ID:20104)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| NVP-BHG712 | PC-3 | CDK2 | NKLTGEVVALKk | Lys1 | 15.3 | 5.00 | uM |
| NVP-BHG712 | PC-3 | CDK2 | LTGEVVALkK | Lys1 | 3.9 | 5.00 | uM |
| NVP-BHG712 | PC-3 | CDK2 | DLkPQNLLINTEGAIK | Lys2 | 15.5 | 5.00 | uM |
| NVP-BHG712 | PC-3 | CDK5 | ETHEIVALkR | Lys1 | 10.0 | 5.00 | uM |
| NVP-BHG712 | PC-3 | CDK5 | NRETHEIVALkR | Lys1 | 21.8 | 5.00 | uM |
| NVP-BHG712 | PC-3 | CDK5 | DLkPQNLLINR | Lys2 | 10.3 | 5.00 | uM |
| NVP-BHG712 | PC-3 | CDK7 | DLkPNNLLLDENGVLK | Lys2 | 12.7 | 5.00 | uM |
| NVP-BHG712 | PC-3 | CDK9 | DMkAANVLITR | Lys2 | 25.4 | 5.00 | uM |
| NVP-BHG712 | PC-3 | CHK1 | LSkGDGLEFK | Other | 12.4 | 5.00 | uM |
| NVP-BHG712 | PC-3 | CHK2 | VAIkIISK | Lys1 | 13.8 | 5.00 | uM |
| NVP-BHG712 | PC-3 | CHK2 | DLkPENVLLSSQEEDCLIK | Lys2 | -3.0 | 5.00 | uM |
| NVP-BHG712 | PC-3 | KC1A | DIkPDNFLMGIGR | Lys2 | 12.1 | 5.00 | uM |
| NVP-BHG712 | PC-3 | CSK | VSDFGLTkEASSTQDTGKLPVK | Activation Loop | 48.9 | 5.00 | uM |
| NVP-BHG712 | PC-3 | CSK | VSDFGLTkEASSTQDTGK | Activation Loop | 46.1 | 5.00 | uM |
| NVP-BHG712 | PC-3 | DGKH | ATFSFCVSPLLVFVNSkSGDNQGVK | ATP | -60.7 | 5.00 | uM |
| NVP-BHG712 | PC-3 | DNAPK | kGGSWIQEINVAEK | ATP | 35.6 | 5.00 | uM |
| NVP-BHG712 | PC-3 | DNAPK | GHDEREHPFLVkGGEDLRQDQR | ATP | -1.8 | 5.00 | uM |
| NVP-BHG712 | PC-3 | eEF2K | YIkYNSNSGFVR | ATP | 3.1 | 5.00 | uM |
| NVP-BHG712 | PC-3 | EGFR | ITDFGLAkLLGAEEK | Activation Loop | -8.1 | 5.00 | uM |
| NVP-BHG712 | PC-3 | EGFR | LLGAEEKEYHAEGGkVPIK | Activation Loop | -15.1 | 5.00 | uM |
| NVP-BHG712 | PC-3 | EGFR | IPVAIkELR | Lys1 | -1.0 | 5.00 | uM |
| NVP-BHG712 | PC-3 | EphA1 | LLDDFDGTYETQGGkIPIR | Activation Loop | 84.5 | 5.00 | uM |
| NVP-BHG712 | PC-3 | EPHA2 | VLEDDPEATYTTSGGkIPIR | Activation Loop | 97.0 | 5.00 | uM |
| NVP-BHG712 | PC-3 | EPHA2 | EVPVAIkTLK | Lys1 | 88.3 | 5.00 | uM |
| NVP-BHG712 | PC-3 | EphA7 | VIEDDPEAVYTTTGGkIPVR | Activation Loop | 32.0 | 5.00 | uM |