XMD-12 KiNativ -- single dose experiment - Dataset (ID:20103)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| XMD-12 | PC-3 | PI4KB | VPHTQAVVLNSkDK | ATP | 0.2 | 10 | uM |
| XMD-12 | PC-3 | GCN2_domain2 | DLkPVNIFLDSDDHVK | Lys2 | 0.2 | 10 | uM |
| XMD-12 | PC-3 | EGFR | IPVAIkELR | Lys1 | -0.3 | 10 | uM |
| XMD-12 | PC-3 | IRAK1 | AIQFLHQDSPSLIHGDIkSSNVLLDER | Lys2 | 0.5 | 10 | uM |
| XMD-12 | PC-3 | MAP3K4 | DIkGANIFLTSSGLIK | Lys2 | -0.6 | 10 | uM |
| XMD-12 | HeLa | IRAK4 | DIkSANILLDEAFTAK | Lys2 | -10.0 | 10 | uM |
| XMD-12 | PC-3 | WNK4 | DLkCDNVFITGPTGSVK | Lys2 | -10.1 | 10 | uM |
| XMD-12 | PC-3 | p38d,p38g | DLkPGNLAVNEDCELK | Lys2 | -10.2 | 10 | uM |
| XMD-12 | HeLa | MAP2K6 | DVkPSNVLINALGQVK | Lys2 | -10.4 | 10 | uM |
| XMD-12 | HeLa | PLK1 | DLkLGNLFLNEDLEVK | Lys2 | 10.9 | 10 | uM |
| XMD-12 | PC-3 | CDK14 | LVALkVIR | Lys1 | 1.1 | 10 | uM |
| XMD-12 | HeLa | ARAF | DLkSNNIFLHEGLTVK | Lys2 | 1.1 | 10 | uM |
| XMD-12 | PC-3 | CDK16 | LTDNLVALkEIR | Lys1 | -11.1 | 10 | uM |
| XMD-12 | HeLa | RSK1,RSK4 domain1 | VLGQGSFGkVFLVR | ATP Loop | -11.2 | 10 | uM |
| XMD-12 | HeLa | TEC | YVLDDQYTSSSGAkFPVK | Activation Loop | 11.2 | 10 | uM |
| XMD-12 | HeLa | CDK2 | DLkPQNLLINTEGAIK | Lys2 | -11.3 | 10 | uM |
| XMD-12 | HeLa | MLTK | WISQDKEVAVKk | Lys1 | 11.4 | 10 | uM |
| XMD-12 | HeLa | PRPK | FLSGLELVkQGAEAR | ATP Loop | -11.6 | 10 | uM |
| XMD-12 | PC-3 | TLK2 | YVAVkIHQLNK | Lys1 | -11.7 | 10 | uM |
| XMD-12 | PC-3 | CK1d,CK1e | DVkPDNFLMGLGKK | Lys2 | 11.8 | 10 | uM |
| XMD-12 | PC-3 | ILK | ISMADVkFSFQCPGR | Protein Kinase Domain | -11.9 | 10 | uM |
| XMD-12 | PC-3 | Wnk1,Wnk2,Wnk4 | IGDLGLATLkR | Activation Loop | -11.9 | 10 | uM |
| XMD-12 | HeLa | MAP2K3 | DVkPSNVLINK | Lys2 | -11.9 | 10 | uM |
| XMD-12 | PC-3 | GCN2 | LDGCCYAVkR | Lys1 | -12.4 | 10 | uM |
| XMD-12 | PC-3 | ILK | WQGIVVkVLK | Lys1 | -12.5 | 10 | uM |