PLX-4720 KiNativ -- dose response experiment - Dataset (ID:20090)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | IC50 | Conc unit |
|---|---|---|---|---|---|---|
| PLX-4720 | A-375 | CDK2 | DLkPQNLLINTEGAIK | LYS2 | >10 | uM |
| PLX-4720 | A-375 | CDK4 | DLkPENILVTSGGTVK | LYS2 | >10 | uM |
| PLX-4720 | A-375 | CDK5 | NVLHRDLkPQNLLINR | LYS2 | >10 | uM |
| PLX-4720 | A-375 | CDK5 | NRETHEIVALkR | LYS1 | >10 | uM |
| PLX-4720 | A-375 | CDK6 | DLkPQNILVTSSGQIK | LYS2 | >10 | uM |
| PLX-4720 | A-375 | CDK7 | DLkPNNLLLDENGVLK | LYS2 | >10 | uM |
| PLX-4720 | A-375 | CDK9 | DMkAANVLITR | LYS2 | >10 | uM |
| PLX-4720 | A-375 | CHK1 | DIkPENLLLDERDNLK | LYS2 | >10 | uM |
| PLX-4720 | A-375 | CHK2 | VAIkIISK | LYS1 | >10 | uM |
| PLX-4720 | A-375 | KC1A | DIkPDNFLMGIGR | LYS2 | >10 | uM |
| PLX-4720 | A-375 | CK1d,CK1e | DVkPDNFLMGLGKK | LYS2 | >10 | uM |
| PLX-4720 | A-375 | CSK | VSDFGLTkEASSTQDTGKLPVK | Activation Loop | 6.4 | uM |
| PLX-4720 | A-375 | CSK | VSDFGLTkEASSTQDTGKLPVKWTAPEALR | Activation Loop | 6.1 | uM |
| PLX-4720 | A-375 | DMPK | DIkPDNILLDR | LYS2 | >10 | uM |
| PLX-4720 | A-375 | DNAPK | kGGSWIQEINVAEK | ATP | >10 | uM |
| PLX-4720 | A-375 | DNAPK | GHDEREHPFLVkGGEDLR | ATP | >10 | uM |
| PLX-4720 | A-375 | DNAPK | EHPFLVkGGEDLR | ATP | >10 | uM |
| PLX-4720 | A-375 | DNAPK | GHDEREHPFLVkGGEDLRQDQR | ATP | >10 | uM |
| PLX-4720 | A-375 | eEF2K | YIkYNSNSGFVRDDNIR | ATP | >10 | uM |
| PLX-4720 | A-375 | eEF2K | YIkYNSNSGFVR | ATP | >10 | uM |
| PLX-4720 | A-375 | EGFR | IPVAIkELR | LYS1 | >10 | uM |
| PLX-4720 | A-375 | EPHA2 | VLEDDPEATYTTSGGkIPIR | Activation Loop | >10 | uM |
| PLX-4720 | A-375 | MK03 | YIHSANVLHRDLkPSNLLINTTCDLK | LYS2 | >10 | uM |
| PLX-4720 | A-375 | MK03 | DLkPSNLLINTTCDLK | LYS2 | >10 | uM |
| PLX-4720 | A-375 | Erk5 | DLkPSNLLVNENCELK | LYS2 | >10 | uM |