PLX-4720 KiNativ -- dose response experiment - Dataset (ID:20090)
Proteins Studied
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| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 200825 | RSKL1_domain1 | 200825 | Q96S38 | Ribosomal protein S6 kinase delta-1 | KiNativ | domain1 | |||
| 200816 | RSK1,RSK2_domain1 | 200816 | Q15418 | Ribosomal protein S6 kinase alpha 1; KS6A1 | KiNativ | domain1 | |||
| 200817 | RSK1_domain1 | 200817 | Q15418 | Ribosomal protein S6 kinase alpha 1; KS6A1 | KiNativ | domain1 | |||
| 200824 | RSK3_domain1 | 200824 | Q15349 | Ribosomal protein S6 kinase alpha-2; S6K-alpha-2; KS6A2; p90-RSK 2; MAPKAPK-1c; pp90RSK3 | KiNativ | domain1 | |||
| 200820 | RSK2_domain1 | 200820 | P51812 | Ribosomal protein S6 kinase alpha 3; KS6A3; S6K-alpha-3; p90-RSK 3; MAPKAPK-1b; pp90RSK2 | KiNativ | domain1 | |||
| 200749 | MSK1,MSK2_domain1 | 200749 | O75582 | Ribosomal protein S6 kinase alpha 5 | KiNativ | domain1 | |||
| 200750 | MSK1_domain1 | 200750 | O75582 | Ribosomal protein S6 kinase alpha 5 | KiNativ | domain1 | |||
| 200815 | RSK1,RSK2,RSK3_domain1 | 200815 | Q15418 | Ribosomal protein S6 kinase alpha 1; KS6A1 | KiNativ | domain1 | |||
| 200818 | RSK1_domain1 | 200818 | Q15418 | Ribosomal protein S6 kinase alpha 1; KS6A1 | KiNativ | domain1 | |||
| 200819 | RSK1_domain2 | 200819 | Q15418 | Ribosomal protein S6 kinase alpha 1; KS6A1 | KiNativ | domain2 | |||
| 200821 | RSK2_domain2 | 200821 | P51812 | Ribosomal protein S6 kinase alpha 3; KS6A3; S6K-alpha-3; p90-RSK 3; MAPKAPK-1b; pp90RSK2 | KiNativ | domain2 | |||
| 200822 | RSK2_domain2 | 200822 | P51812 | Ribosomal protein S6 kinase alpha 3; KS6A3; S6K-alpha-3; p90-RSK 3; MAPKAPK-1b; pp90RSK2 | KiNativ | domain2 | |||
| 200706 | JAK1_domain2 | 200706 | P23458 | Tyrosine-protein kinase JAK1 | KiNativ | domain2 | |||
| 200692 | GCN2_domain2 | 200692 | Q9P2K8 | Eukaryotic translation initiation factor 2-alpha kinase 4 | KiNativ | domain2 | |||
| 200691 | GCN2_domain2 | 200691 | Q9P2K8 | Eukaryotic translation initiation factor 2-alpha kinase 4 | KiNativ | domain2 | |||
| 200705 | JAK1_domain2 | 200705 | P23458 | Tyrosine-protein kinase JAK1 | KiNativ | domain2 | |||
| 200823 | RSK2_domain2 | 200823 | P51812 | Ribosomal protein S6 kinase alpha 3; KS6A3; S6K-alpha-3; p90-RSK 3; MAPKAPK-1b; pp90RSK2 | KiNativ | domain2 | |||
| 200646 | AXL | 200646 | P30530 | Tyrosine-protein kinase receptor UFO precursor | KiNativ | ||||
| 200641 | ARAF | 200641 | P10398 | A-Raf proto-oncogene serine/threonine-protein kinase | KiNativ | ||||
| 200634 | ABL,ARG | 200634 | P00519 | Proto-oncogene tyrosine-protein kinase ABL1 | KiNativ | ||||
| 200640 | AMPKa1,AMPKa2 | 200640 | Q13131 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | KiNativ | ||||
| 200655 | CDK10 | 200655 | Q15131 | Cell division protein kinase 10 | KiNativ | ||||
| 200639 | AMPKa1,AMPKa2 | 200639 | Q13131 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | KiNativ | ||||
| 200633 | ABL,ARG | 200633 | P00519 | Proto-oncogene tyrosine-protein kinase ABL1 | KiNativ | ||||
| 200644 | AurA | 200644 | O14965 | Serine/threonine-protein kinase 6 | KiNativ |