XMD11-85h KINOMEscan - Dataset (ID:20071)
Proteins Studied
Download: Excel (XLSX), Comma-separated (CSV)
| LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
|---|---|---|---|---|---|---|---|---|---|
| 200324 | PIK3CA(C420R) | 200324 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | C420R | Mutation (C420R); Partial length | ||
| 200217 | KIT(D816V) | 200217 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | D816V | Mutation (D816V); Partial length | ||
| 200169 | FLT3(D835H) | 200169 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | D835H | Mutation (D835H); Partial length | ||
| 200170 | FLT3(D835Y) | 200170 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | D835Y | Mutation (D835Y); Partial length | ||
| 200325 | PIK3CA(E542K) | 200325 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | E542K | Mutation (E542K); Partial length | ||
| 200326 | PIK3CA(E545A) | 200326 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | E545A | Mutation (E545A); Partial length | ||
| 200327 | PIK3CA(E545K) | 200327 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | E545K | Mutation (E545K); Partial length | ||
| 200123 | EGFR(E746-A750del) | 200123 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | E746-A750del | Mutation (E746-A750del); Partial length | ||
| 200164 | FGFR3(G697C) | 200164 | P22607 | Fibroblast growth factor receptor 3; ACH; CD333; CEK2; FGFR3; HSFGFR3EX; JTK4 | KINOMEscan | G697C | Mutation (G697C); Partial length | ||
| 200124 | EGFR(G719C) | 200124 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | G719C | Mutation (G719C); Partial length | ||
| 200125 | EGFR(G719S) | 200125 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | G719S | Mutation (G719S); Partial length | ||
| 200328 | PIK3CA(H1047L) | 200328 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | H1047L | Mutation (H1047L); Partial length | ||
| 200329 | PIK3CA(H1047Y) | 200329 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | H1047Y | Mutation (H1047Y); Partial length | ||
| 200171 | FLT3(ITD) | 200171 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | ITD | Mutation (ITD); Partial length | ||
| 200172 | FLT3(K663Q) | 200172 | P36888 | Fms-related tyrosine kinase 3; CD135; FLK2; FLK-2; FLT3; FLT-3; Ly72; STK1 | KINOMEscan | K663Q | Mutation (K663Q); Partial length | ||
| 200218 | KIT(L576P) | 200218 | P10721 | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD117; C-Kit; KIT; PBT; SCFR | KINOMEscan | L576P | Mutation (L576P); Partial length | ||
| 200126 | EGFR(L747-E749del, A750P) | 200126 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L747-E749del, A750P | Mutation (L747-E749del, A750P); Partial length | ||
| 200127 | EGFR(L747-S752del, P753S) | 200127 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L747-S752del, P753S | Mutation (L747-S752del, P753S); Partial length | ||
| 200128 | EGFR(L747-T751del,Sins) | 200128 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L747-T751del,Sins | Mutation (L747-T751del,Sins); Partial length | ||
| 200129 | EGFR(L858R) | 200129 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L858R | Mutation (L858R); Partial length | ||
| 200130 | EGFR(L858R,T790M) | 200130 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L858R,T790M | Mutation (L858R,T790M); Partial length | ||
| 200131 | EGFR(L861Q) | 200131 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L861Q | Mutation (L861Q); Partial length | ||
| 200331 | PIK3CA(M1043I) | 200331 | P42336 | Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; MGC142161; MGC142163; p110-alpha; PI3K; PIK3CA; PI3K-alpha | KINOMEscan | M1043I | Mutation (M1043I); Partial length | ||
| 200260 | MET(M1250T) | 200260 | P08581 | Hepatocyte growth factor receptor; AUTS9; c-Met; HGFR; MET; RCCP2 | KINOMEscan | M1250T | Mutation (M1250T); Partial length | ||
| 200371 | RET(M918T) | 200371 | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret; CDHF12; CDHR16; HSCR1; MEN2A; MEN2B; MTC1; PTC; RET; RET51; RET-ELE1 | KINOMEscan | M918T | Mutation (M918T); Partial length |