KINOMEscan data

KINOMEscan is a biochemical kinase profiling assay that measures drug binding using a panel of ~440 purified kinases. Here, we have assembled a table of all small molecules in the HMS LINCS collection that we have profiled by KINOMEscan, including links to the raw binding data. This table is also available for download as a spreadsheet (.xlsx).
Last Update: September 15, 2016.
 

Primary name Alternative names LINCS Small
Molecule ID
HMS Small
Molecule ID
HMS LINCS 
Dataset ID
5z-7-oxozeaenol LSM-6712 HMSL10356 20211
A443654 LSM-1045 HMSL10045 20059
AC220 LSM-1037 HMSL10037 20147
Afatinib BIBW-2992 LSM-1133 HMSL10133 20172
AG1478 Tyrphostin LSM-1224 HMSL10223 20086
Alpelisib LSM-4256 HMSL10233 20263
ALW-II-38-3 LSM-1002 HMSL10002 20049
ALW-II-49-7 LSM-1003 HMSL10003 20050
AT-7519 LSM-1004 HMSL10004 20191
AZ-628 LSM-1050 HMSL10050 20025
AZD 5438 KIN001-239 LSM-1159 HMSL10158 20135
AZD-6482 KIN001-193 LSM-1059 HMSL10059 20038
AZD1152-HQPA LSM-1067 HMSL10067 20043
AZD1152-HQPA LSM-1067 HMSL10067 20158
AZD4547 LSM-6308 HMSL10289 20129
AZD7762 LSM-1006 HMSL10006 20027
Baricitinib INCB028050; LY3009104 LSM-6709 HMSL10354 20227
BEZ235 NVP-BEZ235 LSM-4255 HMSL10232 20096
BGJ398 KIN001-271; NVP-BGJ398 LSM-1184 HMSL10183 20224
BI-2536 NPK33-1-98-1 LSM-1041 HMSL10041 20057
BI-2536 NPK33-1-98-1 LSM-1041 HMSL10041 20149
BIBF-1120 Vargatef LSM-1152 HMSL10151 20175
BMS-387032 SNS-032 LSM-1132 HMSL10132 20171
BMS-536924 KIN001-126 LSM-1210 HMSL10209 20112
BMS345541 LSM-1028 HMSL10028 20034
BMS345541 LSM-1028 HMSL10028 20146
Bosutinib SKI-606 LSM-1190 HMSL10189 20184
Brivanib BMS-540215 LSM-1178 HMSL10177 20180
BS-181 LSM-6305 HMSL10286 20127
Buparlisib LSM-1148 HMSL10147 20262
BX-912 LSM-1055 HMSL10055 20037
Canertinib CI-1033; PD-183805 LSM-1120 HMSL10120 20118
Canertinib CI-1033; PD-183805 LSM-1120 HMSL10120 20164
CG-930 JNK930 LSM-1058 HMSL10058 20114
CGP60474 MLS000911536; SMR000463552 LSM-1025 HMSL10025 20054
CGP74514A LSM-6711 HMSL10355 20203
CP466722 LSM-1009 HMSL10009 20028
CP724714 LSM-1010 HMSL10010 20029
Crizotinib PF02341066 LSM-1027 HMSL10027 20033
Crizotinib PF02341066 LSM-1027 HMSL10027 20200
CYT387 Momelotinib LSM-1141 HMSL10140 20082
Dabrafenib GSK2118436 LSM-6303 HMSL10284 20131
Dasatinib BMS-354825; Sprycel LSM-1020 HMSL10020 20196
Dinaciclib SCH727965 LSM-6306 HMSL10287 20128
Dovitinib TKI_258; TKI258 LSM-1127 HMSL10127 20168
Enzastaurin LY317615 LSM-1069 HMSL10069 20159
Erlotinib OSI-774 LSM-1097 HMSL10097 20160
Flavopiridol Alvocidib; HMR-1275; L868275 LSM-1011 HMSL10011 20193
Foretinib XL880; GSK1363089 LSM-1158 HMSL10157 20176
GDC-0879 LSM-1182 HMSL10181 20181
GDC-0941 LSM-1047 HMSL10047 20060
GDC-0941 LSM-1047 HMSL10047 20152
GDC-0941 LSM-1047 HMSL10047 20261
Gefitinib ZD1839; Iressa LSM-1098 HMSL10098 20161
GSK 690693 LSM-1128 HMSL10128 20169
GSK1059615 LSM-1173 HMSL10172 20085
GSK1838705 LSM-4276 HMSL10255 20190
GSK2126458 LSM-1147 HMSL10146 20084
GSK429286A LSM-1012 HMSL10012 20030
GSK461364 LSM-1013 HMSL10013 20031
GSK461364 LSM-1013 HMSL10013 20194
GW-5074 LSM-1029 HMSL10029 20022
GW843682 LSM-1014 HMSL10014 20032
HG-14-10-04 LSM-6345 HMSL10342 20134
HG-14-8-02 LSM-6344 HMSL10341 20133
HG-5-113-01 LSM-1015 HMSL10015 20051
HG-5-88-01 LSM-1016 HMSL10016 20052
HG-6-64-01 KIN001-206 LSM-1017 HMSL10017 20021
HG-9-91-01 LSM-6343 HMSL10340 20132
Ibrutinib PCI-32765 LSM-1129 HMSL10129 20222
Imatinib Gleevec; Glivec; CGP-57148B; STI-571 LSM-1023 HMSL10023 20198
JNK-9L KIN001-204 LSM-1100 HMSL10100 20048
JNK-IN-5A TCS JNK 5a; KIN001-188 LSM-1209 HMSL10208 20081
JW-7-24-1 LSM-1019 HMSL10019 20108
JWE-035 LSM-1092 HMSL10092 20046
Ki20227 LSM-1188 HMSL10187 20183
KIN001-021 CGP082996; CINK4; ZINC01493715 LSM-1213 HMSL10212 20225
KIN001-111 A770041 LSM-1214 HMSL10213 20113
KIN001-123 WZ-1-84 LSM-1215 HMSL10214 20119
KIN001-127 LSM-1043 HMSL10043 20058
KIN001-220 Genentech 10 LSM-1065 HMSL10065 20041
KIN001-242 FMK LSM-1044 HMSL10044 20151
KU63794 LSM-1230 HMSL10229 20117
KW2449 KW-2449 LSM-1193 HMSL10192 20185
Lapatinib GW-572016; Tykerb LSM-1051 HMSL10051 20107
Lapatinib GW-572016; Tykerb LSM-1051 HMSL10051 20155
Lestaurtinib CEP-701 LSM-1231 HMSL10230 20189
Linifanib ABT-869; AL-39324 LSM-1183 HMSL10182 20182
Masitinib AB1010 LSM-1130 HMSL10130 20170
MLN8054 LSM-1066 HMSL10066 20042
MLN8054 LSM-1066 HMSL10066 20157
Motesanib AMG706 LSM-1042 HMSL10042 20150
MPS-1-IN-1 HG-5-125-01 LSM-1105 HMSL10105 20221
MRT67307 LSM-36387 HMSL10364 20228
Neratinib HKI-272 LSM-1018 HMSL10018 20053
Neratinib HKI-272 LSM-1018 HMSL10018 20195
Nilotinib AMN-107 LSM-1099 HMSL10099 20162
NPK76-II-72-1 LSM-1070 HMSL10070 20061
NU7441 KU 57788 LSM-1061 HMSL10061 20040
NVP-TAE684 LSM-1024 HMSL10024 20109
NVP-TAE684 LSM-1024 HMSL10024 20199
OTSSP167 LSM-6340 HMSL10337 20130
Pazopanib GW786034; Votrient LSM-1114 HMSL10114 20163
PD0325901 PD-325901 LSM-1101 HMSL10101 20080
PD0332991 LSM-1071 HMSL10071 20044
PD173074 LSM-1026 HMSL10026 20055
PD184352 CI-1040 LSM-1048 HMSL10048 20153
PHA-665752 LSM-1125 HMSL10125 20166
PHA-767491 LSM-6304 HMSL10285 20126
PHA-793887 LSM-1073 HMSL10073 20125
PI103 LSM-1126 HMSL10126 20167
PKC412 LSM-1221 HMSL10220 20187
PLX-4720 LSM-1049 HMSL10049 20024
PLX-4720 LSM-1049 HMSL10049 20154
PLX4032 RG7204; R7204; RO5185426 LSM-1068 HMSL10068 20026
QL-X-138 LSM-1075 HMSL10075 20062
QL-XI-92 LSM-1076 HMSL10076 20063
(R)-Roscovitine CYC202; Seliciclib LSM-1001 HMSL10001 20124
R406 LSM-1040 HMSL10040 20110
R406 LSM-1040 HMSL10040 20148
RAF 265 CHIR-265 LSM-1207 HMSL10206 20201
RO-3306 LSM-1104 HMSL10104 20202
Ruxolitinib LSM-1139 HMSL10138 20173
SB 203580 RWJ 64809; PB 203580 LSM-1168 HMSL10167 20177
SB590885 LSM-1046 HMSL10046 20023
Selumetinib AZD6244; Array142886 LSM-1056 HMSL10056 20156
SGX523 LSM-1123 HMSL10123 20165
Sigma A6730 KIN001-102; AKT inhibitor VIII; Akt1/2 kinase inhibitor LSM-1035 HMSL10035 20083
Sorafenib BAY-439006 LSM-1008 HMSL10008 20020
Sorafenib BAY-439006 LSM-1008 HMSL10008 20192
SP600125 LSM-1163 HMSL10162 20111
Sunitinib Sutent; SU11248 LSM-1176 HMSL10175 20179
Taselisib HMSL10445 20264
TAK-715 LSM-1060 HMSL10060 20039
TG 101348 LSM-1142 HMSL10141 20174
TGX221 LSM-1172 HMSL10171 20223
Tofacitinib Tasocitinib; CP-690550; Xeljanz LSM-1227 HMSL10226 20188
Torin1 LSM-1079 HMSL10079 20064
Torin2 LSM-1080 HMSL10080 20065
Tozasertib VX680; MK-0457 LSM-1021 HMSL10021 20197
Vandetanib ZD6474; Zactima; Caprelsa LSM-1199 HMSL10198 20186
VX-745 LSM-1169 HMSL10168 20178
WH-4-023 LSM-1038 HMSL10038 20036
WH-4-025 LSM-1039 HMSL10039 20056
WYE-125132 LSM-1064 HMSL10064 20079
WZ-4-145 LSM-1082 HMSL10082 20066
WZ-7043 LSM-1083 HMSL10083 20067
WZ3105 LSM-1084 HMSL10084 20068
WZ4002 LSM-1085 HMSL10085 20069
XMD-12 LSM-1106 HMSL10106 20115
XMD11-50 LRRK2-in-1 LSM-1086 HMSL10086 20070
XMD11-85h LSM-1087 HMSL10087 20071
XMD13-2 LSM-1088 HMSL10088 20072
XMD14-99 LSM-1089 HMSL10089 20073
XMD15-27 LSM-1090 HMSL10090 20074
XMD16-144 LSM-1091 HMSL10091 20075
XMD8-85 LSM-1093 HMSL10093 20076
XMD8-92 LSM-1094 HMSL10094 20077
ZG-10 LSM-1095 HMSL10095 20078
ZM-447439 LSM-1096 HMSL10096 20047
ZSTK474 LSM-1053 HMSL10053 20220