JNJ-10198409 - Small Molecule (ID:10467-101)

HMS LINCS ID: 10467-101
Name: JNJ-10198409
Alternative Names: PDGF receptor tyrosine kinase inhibitor IV
LINCS ID:
PubChem CID: 9797370
ChEBI ID:
ChEMBL ID:
Molecular Mass: 325.12
InChi: InChI=1S/C18H16FN3O2/c1-23-15-7-10-6-14-17(13(10)9-16(15)24-2)21-22-18(14)20-12-5-3-4-11(19)8-12/h3-5,7-9H,6H2,1-2H3,(H2,20,21,22)
InChi Key: ZDNURMVOKAERHZ-UHFFFAOYSA-N
SMILES: COC1=C(C=C2C(=C1)CC3=C2NN=C3NC4=CC(=CC=C4)F)OC
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
ABL1, PDGFRA, PDGFRB
2
(equivalent to 100 nM ≤ Kd < 1µM)
FYN, LCK, SRC
3
(equivalent to 1µM ≤ Kd < 10 µM)
CSNK1A1, CSNK1D, CSNK1E, CSNK1G1, CSNK1G2, FLT1, FLT4, KDR
10
(confirmed non-binding)
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Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20000
Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library.
Analysis

Batch Information:

HMS LINCS Batch ID Provider Provider Batch ID
10467-101-1 EMD Millipore D00168560