Staurosporine aglycone - Small Molecule (ID:10454-101)

HMS LINCS ID: 10454-101
Name: Staurosporine aglycone
Alternative Names: K252C
LINCS ID:
PubChem CID: 3815
ChEBI ID:
ChEMBL ID:
Molecular Mass: 311.11
InChi: InChI=1S/C20H13N3O/c24-20-17-12(9-21-20)15-10-5-1-3-7-13(10)22-18(15)19-16(17)11-6-2-4-8-14(11)23-19/h1-8,22-23H,9H2,(H,21,24)
InChi Key: MEXUTNIFSHFQRG-UHFFFAOYSA-N
SMILES: C1C2=C3C4=CC=CC=C4NC3=C5C(=C2C(=O)N1)C6=CC=CC=C6N5
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
JAK3, MAP3K11
2
(equivalent to 100 nM ≤ Kd < 1µM)
CAMK2A, CAMK2B, CAMK2D, CAMK2G, CCND1, CDK4, MAP3K9, Prkca, PRKCA, Prkcb, PRKCB, Prkcd, PRKCD, Prkce, PRKCE, Prkcg, PRKCG, Prkch, PRKCH, PRKCI, Prkcq, PRKCQ, Prkcz, PRKCZ, PRKG1
3
(equivalent to 1µM ≤ Kd < 10 µM)
CCNE1, CCNE2, CDK2, GLI1, GLI2, PKD1, PRKACA, PRKD1, PRKD3
10
(confirmed non-binding)
(Click to show)

Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20000
Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library.
Analysis

Batch Information:

HMS LINCS Batch ID Provider Provider Batch ID
10454-101-1 EMD Millipore D00176697