Poziotinib - Small Molecule (ID:10397-101)

HMS LINCS ID: 10397-101
Name: Poziotinib
Alternative Names: HM781-36B; NOV120101
LINCS ID:
PubChem CID: 25127713
ChEBI ID:
ChEMBL ID:
Molecular Mass: 490.10
InChi: InChI=1S/C23H21Cl2FN4O3/c1-3-20(31)30-8-6-13(7-9-30)33-19-10-14-17(11-18(19)32-2)27-12-28-23(14)29-16-5-4-15(24)21(25)22(16)26/h3-5,10-13H,1,6-9H2,2H3,(H,27,28,29)
InChi Key: LPFWVDIFUFFKJU-UHFFFAOYSA-N
SMILES: COC1=C(C=C2C(=C1)N=CN=C2NC3=C(C(=C(C=C3)Cl)Cl)F)OC4CCN(CC4)C(=O)C=C
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
2
(equivalent to 100 nM ≤ Kd < 1µM)
EGFR, ERBB2, ERBB4

Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20000
Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library.
Analysis

Batch Information:

HMS LINCS Batch ID Provider Provider Batch ID
10397-101-1 MedChem Express 15405