XL019 - Small Molecule (ID:10388-101)

HMS LINCS ID: 10388-101
Name: XL019
Alternative Names:
LINCS ID:
PubChem CID: 57990869
ChEBI ID:
ChEMBL ID:
Molecular Mass: 444.23
InChi: InChI=1S/C25H28N6O2/c32-24(23-2-1-12-26-23)28-19-5-3-18(4-6-19)22-11-13-27-25(30-22)29-20-7-9-21(10-8-20)31-14-16-33-17-15-31/h3-11,13,23,26H,1-2,12,14-17H2,(H,28,32)(H,27,29,30)/t23-/m0/s1
InChi Key: ISOCDPQFIXDIMS-QHCPKHFHSA-N
SMILES: O=C([C@H]1NCCC1)NC2=CC=C(C3=NC(NC4=CC=C(N5CCOCC5)C=C4)=NC=C3)C=C2
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
JAK2
2
(equivalent to 100 nM ≤ Kd < 1µM)
FLT1, FLT3, FLT4, IKBKB, JAK1, JAK3, KDR, KIT, MAP3K9, PDGFRA, PDGFRB, RPS6KB1, TYK2

Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20000
Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library.
Analysis

Batch Information:

HMS LINCS Batch ID Provider Provider Batch ID
10388-101-1 MedChem Express 10347