Entospletinib - Small Molecule (ID:10372-101)

HMS LINCS ID: 10372-101
Name: Entospletinib
Alternative Names: GS9973
LINCS ID:
PubChem CID: 59473233
ChEBI ID:
ChEMBL ID:
Molecular Mass: 411.18
InChi: InChI=1S/C23H21N7O/c1-2-17-14-25-28-20(17)13-16(1)21-15-30-8-7-24-23(30)22(27-21)26-18-3-5-19(6-4-18)29-9-11-31-12-10-29/h1-8,13-15H,9-12H2,(H,25,28)(H,26,27)
InChi Key: XSMSNFMDVXXHGJ-UHFFFAOYSA-N
SMILES: C1COCCN1C2=CC=C(C=C2)NC3=NC(=CN4C3=NC=C4)C5=CC6=C(C=C5)C=NN6
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
2
(equivalent to 100 nM ≤ Kd < 1µM)
FLT3, JAK2, Kit, SYK
3
(equivalent to 1µM ≤ Kd < 10 µM)
KDR, RET, Syk

Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20000
Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library.
Analysis

Batch Information:

HMS LINCS Batch ID Provider Provider Batch ID
10372-101-1 MedChem Express 11593