Entospletinib - Small Molecule (ID:10372-101)
| HMS LINCS ID: |
10372-101
|
| Name: | Entospletinib |
| Alternative Names: | GS9973 |
| LINCS ID: | |
| PubChem CID: | 59473233 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 411.18 |
| InChi: | InChI=1S/C23H21N7O/c1-2-17-14-25-28-20(17)13-16(1)21-15-30-8-7-24-23(30)22(27-21)26-18-3-5-19(6-4-18)29-9-11-31-12-10-29/h1-8,13-15H,9-12H2,(H,25,28)(H,26,27) |
| InChi Key: | XSMSNFMDVXXHGJ-UHFFFAOYSA-N |
| SMILES: | C1COCCN1C2=CC=C(C=C2)NC3=NC(=CN4C3=NC=C4)C5=CC6=C(C=C5)C=NN6 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
FLT3, JAK2, Kit, SYK | |
3 (equivalent to 1µM ≤ Kd < 10 µM) | KDR, RET, Syk |
Batch Information for HMSL10372-101-1:
| HMS LINCS Batch ID: | 10372-101-1 |
| Provider: | MedChem Express |
| Provider Batch ID: | 11593 |
| Salt: | 101 |
| Molecular Formula: | C23H21N7O |
| Molecular Weight: | 411.46 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2015-08-27 |
| Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10372-101-1:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 08/31/2015 | PASS | HMSL10372-101-1_LCMS.pdf |
(equivalent to 100 nM ≤ Kd < 1µM)