AZD5363 - Small Molecule (ID:10370-101)

HMS LINCS ID: 10370-101
Name: AZD5363
Alternative Names:
LINCS ID:
PubChem CID: 25227436
ChEBI ID:
ChEMBL ID:
Molecular Mass: 428.17
InChi: InChI=1S/C21H25ClN6O2/c22-15-3-1-14(2-4-15)17(6-12-29)27-20(30)21(23)7-10-28(11-8-21)19-16-5-9-24-18(16)25-13-26-19/h1-5,9,13,17,29H,6-8,10-12,23H2,(H,27,30)(H,24,25,26)/t17-/m0/s1
InChi Key: JDUBGYFRJFOXQC-KRWDZBQOSA-N
SMILES: O=C(C1(N)CCN(C2=C3C(NC=C3)=NC=N2)CC1)N[C@H](C4=CC=C(Cl)C=C4)CCO
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
AKT1, AKT2, AKT3, ROCK2
2
(equivalent to 100 nM ≤ Kd < 1µM)
ROCK1

Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20000
Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library.
Analysis

Batch Information:

HMS LINCS Batch ID Provider Provider Batch ID
10370-101-1 MedChem Express 09523