GSK-J2 - Small Molecule (ID:10322-110)

HMS LINCS ID: 10322-110
Name: GSK-J2
Alternative Names:
LINCS ID: LSM-6327
PubChem CID:
ChEBI ID:
ChEMBL ID:
Molecular Mass: 388.18
InChi: InChI=1S/C22H23N5O2/c28-21(29)7-11-24-19-14-20(26-22(25-19)18-6-3-10-23-15-18)27-12-8-16-4-1-2-5-17(16)9-13-27/h1-6,10,14-15H,7-9,11-13H2,(H,28,29)(H,24,25,26)/p-1
InChi Key: LJIFOCRGDDQFJF-UHFFFAOYSA-M
SMILES: C1CN(CCC2=CC=CC=C21)C3=CC(=NC(=N3)C4=CN=CC=C4)NCCC(=O)[O-]
Relevant Citations:
Date Publicly Available:
Most Recent Update: 2016-04-04

Nominal Targets:

Small Molecule Protein Effective Concentration Key References
GSK-J2 KDM6B
Nature, 2012, 488, pp404–408

Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20000
LINCS Compound Protein Targets and Concentrations
Nominal Targets
20276
Protein levels measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with Vemurafenib in combination with chromatin-targeting compounds (immunofluorescence dataset 3 of 4)
Microscopy/Imaging

Batch Information:

HMS LINCS Batch ID Provider Provider Catalog ID Provider Batch ID
10322-110-1 Cayman Chemical 12056 0445881-1