BMS-754807 - Small Molecule (ID:10290-101)

HMS LINCS ID: 10290-101
Name: BMS-754807
Alternative Names:
LINCS ID: LSM-6218
PubChem CID: 24785538
ChEBI ID:
ChEMBL ID: 575448
Molecular Mass: 461.21
InChi: InChI=1S/C23H24FN9O/c1-23(21(34)26-15-7-8-18(24)25-13-15)9-3-10-32(23)22-28-20(17-4-2-11-33(17)31-22)27-19-12-16(29-30-19)14-5-6-14/h2,4,7-8,11-14H,3,5-6,9-10H2,1H3,(H,26,34)(H2,27,28,29,30,31)/t23-/m0/s1
InChi Key: LQVXSNNAFNGRAH-QHCPKHFHSA-N
SMILES: C[C@]1(CCCN1C2=NN3C=CC=C3C(=N2)NC4=NNC(=C4)C5CC5)C(=O)NC6=CN=C(C=C6)F
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
Akt1, Igf1r, IGF1R
2
(equivalent to 100 nM ≤ Kd < 1µM)
INSR
3
(equivalent to 1µM ≤ Kd < 10 µM)
CCNE1, CCNE2, CDK2
10
(confirmed non-binding)

Batch Information for HMSL10290-101-1:

HMS LINCS Batch ID: 10290-101-1
Provider: ChemieTek
Provider Batch ID: CT-001
Salt: 101
Molecular Formula: C23H24FN9O
Molecular Weight: 461.49
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2013-03-04
Most Recent Update: 2016-08-02