SB-3CT - Small Molecule (ID:10274-101)

HMS LINCS ID: 10274-101
Name: SB-3CT
Alternative Names:
LINCS ID: LSM-4293
PubChem CID: 9883002
ChEBI ID:
ChEMBL ID:
Molecular Mass: 306.04
InChi: InChI=1S/C15H14O3S2/c16-20(17,11-14-10-19-14)15-8-6-13(7-9-15)18-12-4-2-1-3-5-12/h1-9,14H,10-11H2
InChi Key: LSONWRHLFZYHIN-UHFFFAOYSA-N
SMILES: C1C(S1)CS(=O)(=O)C2=CC=C(C=C2)OC3=CC=CC=C3
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
MMP14, MMP2
2
(equivalent to 100 nM ≤ Kd < 1µM)
MMP9
3
(equivalent to 1µM ≤ Kd < 10 µM)
ADAM17
10
(confirmed non-binding)
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Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20000
Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library.
Analysis
20268
Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates.
Analysis
20269
Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics.
Analysis
20270
Growth rate-corrected (GR) dose-response metric signatures across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 3 of 4: Median, upper quartile, and lower quartile GR metrics per perturbagen.
Analysis

Batch Information:

HMS LINCS Batch ID Provider Provider Batch ID
10274-101-1 Enzo Life Sciences