Glycyl-H-1152 - Small Molecule (ID:10253-102)

HMS LINCS ID: 10253-102
Name: Glycyl-H-1152
Alternative Names:
LINCS ID: LSM-4274
PubChem CID:
ChEBI ID:
ChEMBL ID:
Molecular Mass: 376.16
InChi: InChI=1S/C18H24N4O3S/c1-13-7-8-20-15-5-3-6-16(18(13)15)26(24,25)22-10-4-9-21(12-14(22)2)17(23)11-19/h3,5-8,14H,4,9-12,19H2,1-2H3/t14-/m0/s1
InChi Key: SKZNXANHXFSDNA-AWEZNQCLSA-N
SMILES: NCC(N(C[C@@H]1C)CCCN1S(C2=CC=CC3=NC=CC(C)=C32)(=O)=O)=O
Relevant Citations:
Date Publicly Available:
Most Recent Update: 2016-05-06

Nominal Targets:

Small Molecule Protein Effective Concentration Key References
Glycyl-H-1152 ROCK2
11.8 nM
Biochim Biophys Acta. 2005 Dec 30;1754(1-2):245-52.

Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20000
LINCS Compound Protein Targets and Concentrations
Nominal Targets
20268
Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates.
Analysis
20269
Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics.
Analysis
20270
Growth rate-corrected (GR) dose-response metric signatures across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 3 of 4: Median, upper quartile, and lower quartile GR metrics per perturbagen.
Analysis

Batch Information:

HMS LINCS Batch ID Provider Provider Catalog ID Provider Batch ID
10253-102-1 Tocris 2485