IKK16 - Small Molecule (ID:10228-102)

HMS LINCS ID: 10228-102
Name: IKK16
Alternative Names:
LINCS ID: LSM-2309
PubChem CID: 9549298
ChEBI ID:
ChEMBL ID:
Molecular Mass: 483.21
InChi: InChI=1S/C28H29N5OS/c34-27(33-17-12-23(13-18-33)32-15-3-4-16-32)20-7-9-22(10-8-20)30-28-29-14-11-24(31-28)26-19-21-5-1-2-6-25(21)35-26/h1-2,5-11,14,19,23H,3-4,12-13,15-18H2,(H,29,30,31)
InChi Key: BWZJBXAPRCVCKQ-UHFFFAOYSA-N
SMILES: C1CCN(C1)C2CCN(CC2)C(=O)C3=CC=C(C=C3)NC4=NC=CC(=N4)C5=CC6=CC=CC=C6S5
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
IKBKB
2
(equivalent to 100 nM ≤ Kd < 1µM)
AURKA, AURKB, BRSK2, BTK, CAMK1, CDK2, CHEK1, CHUK, CLK2, CSK, CSNK2A1, CSNK2A2, CSNK2B, DAPK1, DYRK1A, DYRK2, DYRK3, EPHA2, EPHA4, EPHB1, EPHB2, EPHB3, EPHB4, FGFR1, FLT1, GCK, GSK3B, HIPK1, HIPK2, HIPK3, IGF1R, IKBKE, INSR, INSRR, JAK2, LCK, MAP2K1, MAP2K1, MAP3K11, MAP3K7, MAPK11, MAPK15, MAPK8, MARK3, MINK1, MKNK1, NTRK1, NUAK1, PAK5, PHKA2, PIM1, PIM3, PKD1, PKN2, PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKCA, PRKCA, RIPK2, ROCK2, RPS6KA1, RPS6KB1, SGK1, SRC, SRC, STK3, SYK, TAOK1, TBK1, YES1
10
(confirmed non-binding)
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Batch Information for HMSL10228-102-1:

HMS LINCS Batch ID: 10228-102-1
Provider: Tocris
Provider Batch ID: reference date: Oct 2010
Salt: 102
Molecular Formula: C28H30ClN5OS
Molecular Weight: 520.09
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2012-08-15
Most Recent Update: 2016-04-04