AG1478 - Small Molecule (ID:10223-101)

HMS LINCS ID: 10223-101
Name: AG1478
Alternative Names: Tyrphostin
LINCS ID: LSM-1224
PubChem CID: 2051
ChEBI ID:
ChEMBL ID:
Molecular Mass: 315.08
InChi: InChI=1S/C16H14ClN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)
InChi Key: GFNNBHLJANVSQV-UHFFFAOYSA-N
SMILES: COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Cl)OC
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
EGFR
2
(equivalent to 100 nM ≤ Kd < 1µM)
ABL1, ABL2, GAK, MAPK14, MKNK1
3
(equivalent to 1µM ≤ Kd < 10 µM)
FBP1, SRC
10
(confirmed non-binding)
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Batch Information for HMSL10223-101-1:

HMS LINCS Batch ID: 10223-101-1
Provider: Santa Cruz Biotechnology
Provider Batch ID: B2312
Salt: 101
Molecular Formula: C16H14ClN3O2
Molecular Weight: 315.75
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2011-07-15
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10223-101-1:

Date HMS QC Outcome Comment Files
04/13/2015 PASS HMSL10223-101-1_LCMS.pdf