GSK429286A - Small Molecule (ID:10012-101)

HMS LINCS ID: 10012-101
Name: GSK429286A
Alternative Names:
LINCS ID: LSM-1012
PubChem CID: 11373846
ChEBI ID:
ChEMBL ID:
Molecular Mass: 432.12
InChi: InChI=1S/C21H16F4N4O2/c1-10-19(20(31)28-17-6-12-9-26-29-16(12)8-15(17)22)14(7-18(30)27-10)11-2-4-13(5-3-11)21(23,24)25/h2-6,8-9,14H,7H2,1H3,(H,26,29)(H,27,30)(H,28,31)
InChi Key: OLIIUAHHAZEXEX-UHFFFAOYSA-N
SMILES: CC1=C(C(CC(=O)N1)C2=CC=C(C=C2)C(F)(F)F)C(=O)NC3=C(C=C4C(=C3)C=NN4)F
Relevant Citations:
Date Publicly Available:
Most Recent Update: 2016-04-04

Nominal Targets:

Small Molecule Protein Effective Concentration Key References
GSK429286A ROCK1
14 nM
[1] Biochem J. 2009 Oct 23;424(1):47-60. PMID: 19740074; [2] J Med Chem. 2007 Jan 11;50(1):6-9. PMID: 17201405

Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20000
LINCS Compound Protein Targets and Concentrations
Nominal Targets
20030
GSK429286A KINOMEscan
KINOMEscan

KINOMEscan Image

Batch Information:

HMS LINCS Batch ID Provider Provider Catalog ID Provider Batch ID
10012-101-1 Haoyuan chemexpress HY-11000 HY-999-20100817
10012-101-2 Haoyuan chemexpress HY-11000 HY-11000-20130427