Tivozanib - Small Molecule (ID:10005-101)

HMS LINCS ID: 10005-101
Name: Tivozanib
Alternative Names: AV-951
LINCS ID: LSM-1005
PubChem CID: 9911830
ChEBI ID:
ChEMBL ID:
Molecular Mass: 454.10
InChi: InChI=1S/C22H19ClN4O5/c1-12-8-21(27-32-12)26-22(28)25-16-5-4-13(9-15(16)23)31-18-6-7-24-17-11-20(30-3)19(29-2)10-14(17)18/h4-11H,1-3H3,(H2,25,26,27,28)
InChi Key: SPMVMDHWKHCIDT-UHFFFAOYSA-N
SMILES: CC1=CC(=NO1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)Cl
Relevant Citations:
Date Publicly Available:
Most Recent Update: 2016-04-04

Nominal Targets:

Small Molecule Protein Effective Concentration Key References
Tivozanib VEGFR-2
[1] Drugs Fut. 2009, 34(10): 793; [2] Cancer Res. 2006 Sep 15;66(18):9134-42. PMID: 16982756

Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20000
LINCS Compound Protein Targets and Concentrations
Nominal Targets

Batch Information:

HMS LINCS Batch ID Provider Provider Catalog ID Provider Batch ID
10005-101-1 Haoyuan chemexpress HY-10977 HY-999-20101221