Proteins
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LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
---|---|---|---|---|---|---|---|---|---|
200490 | Aurora kinase B | 200490 | Q96GD4 | Aurora 1; Aurora- and IPL1-like midbody-associated protein 1; AIM-1; Aurora/IPL1-related kinase 2; ARK-2; Aurora-related kinase 2; STK-1; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 5; Serine/threonine-protein kinase aurora-B | |||||
200491 | Aurora kinase C | 200491 | Q9UQB9 | Aurora 3; Aurora/IPL1-related kinase 3; ARK-3; Aurora-related kinase 3; Aurora/IPL1/Eg2 protein 2; Serine/threonine-protein kinase 13; Serine/threonine-protein kinase aurora-C | |||||
200492 | BAD | 200492 | Q92934 | Bcl2 antagonist of cell death | |||||
200493 | BCL2 | 200493 | P10415 | Apoptosis regulator Bcl-2 | |||||
200494 | BRAF | 200494 | P15056 | Serine/threonine-protein kinase B-raf; v-raf murine sarcoma viral oncogene homolog B1; BRAF1; RAFB1 | |||||
200495 | c-Abl | 200495 | P00519 | Tyrosine-protein kinase ABL1 | |||||
200496 | CDC2 [deprecated record] | 200496 | P06493 | Cyclin-dependent kinase 1 | |||||
200497 | Cdc25 | 200497 | Q13972 | Ras-specific guanine nucleotide-releasing factor 1 | |||||
200498 | CDK1 | 200498 | P06493 | Cyclin-dependent kinase 1; Cell division control protein 2 homolog; Cell division protein kinase 1; p34 protein kinase | |||||
200499 | CHK1 | 200499 | O14757 | Serine/threonine-protein kinase Chk1; CHK1 checkpoint homolog | |||||
200267 | MLK1 | 200267 | P80192 | Mitogen-activated protein kinase kinase kinase 9; MAP3K9; MEKK9; MLK1; PRKE1 | KINOMEscan | Wild Type; Partial length | |||
200266 | MLCK | 200266 | Q32MK0 | Myosin light chain kinase 3; caMLCK; MGC126319; MGC126320; MLCK; MLCK2; MYLK3 | KINOMEscan | Wild Type; Partial length | |||
200131 | EGFR(L861Q) | 200131 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L861Q | Mutation (L861Q); Partial length | ||
200265 | MKNK2 | 200265 | Q9HBH9 | MAP kinase interacting serine/threonine kinase 2; GPRK7; MKNK2; MNK2 | KINOMEscan | Wild Type; Partial length | |||
200264 | MKNK1 | 200264 | Q9BUB5 | MAP kinase interacting serine/threonine kinase 1; MKNK1; MNK1 | KINOMEscan | Wild Type; Full length | |||
200130 | EGFR(L858R,T790M) | 200130 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L858R,T790M | Mutation (L858R,T790M); Partial length | ||
200063 | CAMK2A | 200063 | Q9UQM7 | Calcium/calmodulin-dependent protein kinase II alpha; CAMK2A; CAMKA; KIAA0968 | KINOMEscan | Wild Type; Partial length | |||
200031 | ACVRL1 | 200031 | P37023 | Activin A receptor type II-like 1; ACVRL1; ACVRLK1; ALK1; ALK-1; HHT; HHT2; ORW2; SKR3; TSR-I | KINOMEscan | Wild Type; Partial length | |||
200014 | ABL1(M351T) | 200014 | P00519 | C-abl oncogene 1, receptor tyrosine kinase; ABL; ABL1; bcr/abl; c-ABL; JTK7; p150; v-abl | KINOMEscan | M351T | |||
200263 | MP2K7 | 200263 | O14733 | Dual specificity mitogen-activated protein kinase kinase 7; MKK7 | KINOMEscan | Wild Type; Full length | |||
200262 | MINK | 200262 | Q8N4C8 | Misshapen-like kinase 1 (zebrafish); B55; hMINK; hMINKbeta; MAP4K6; MGC21111; MINK; MINK/ZC3; MINK1; YSK2; ZC3 | KINOMEscan | Wild Type; Partial length | |||
200129 | EGFR(L858R) | 200129 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L858R | Mutation (L858R); Partial length | ||
200261 | MET(Y1235D) | 200261 | P08581 | Hepatocyte growth factor receptor; AUTS9; c-Met; HGFR; MET; RCCP2 | KINOMEscan | Y1235D | Mutation (Y1235D); Partial length | ||
200260 | MET(M1250T) | 200260 | P08581 | Hepatocyte growth factor receptor; AUTS9; c-Met; HGFR; MET; RCCP2 | KINOMEscan | M1250T | Mutation (M1250T); Partial length | ||
200128 | EGFR(L747-T751del,Sins) | 200128 | P00533 | Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); EGFR; ERBB; ERBB1; HER1; mENA; PIG61 | KINOMEscan | L747-T751del,Sins | Mutation (L747-T751del,Sins); Partial length |