Breast Cancer Deubiquitinating Enzyme (DUB) Inhibitor Profiling: Fixed-cell GR measures of 21 breast cell lines to 32 small molecule perturbagens. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20351)

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Cell Small Molecule Treatment Duration GR50 GRmax GR_AOC GEC50 GRinf hGR
BT-20 1247825-37-1 72
10.843923028
-0.5078 0.1707 13.0472 -0.4829 3.6541
BT-20 USP7-IN-1 72
67.2869814403
0.7451 0.0229 80.6417 -0.3763 3.0994
BT-20 GW7647 72
inf
0.7093 -0.0625 0.0000 1.0000 0.0100
BT-20 HBX19818 72
30.8921915642
-0.2433 0.0631 35.1813 -0.4578 5.0000
BT-20 HBX 41108 72
0.575869637316
-0.5895 0.6999 1.0838 -0.5642 1.1945
BT-20 HY-17541A 72
9.75522426236
-0.8815 0.3328 13.7782 -0.9458 3.0751
BT-20 HY-17542 72
inf
1.0099 -0.0181 0.0000 1.0000 0.0100
BT-20 HY-50736 72
0.154452624267
-0.4430 0.9442 0.2491 -0.5003 1.4504
BT-20 HY-50737A 72
0.556969018793
-0.5469 0.6980 0.9349 -0.5102 1.3577
BT-20 IU1 72
inf
1.1490 -0.1850 0.0000 1.0000 0.0100
BT-20 LDN57444 72
0.273589049961
-0.5384 0.7238 0.4768 -0.3750 1.0074
BT-20 MI-2 72
0.409633050522
-0.7406 0.9227 0.6203 -0.7720 2.2499
BT-20 ML-323 72
211.396631725
0.7311 0.0653 1563.4058 -1.0000 0.5491
BT-20 Pevonedistat 72
0.777542936783
-0.2693 0.5455 0.9974 -0.2189 1.4577
BT-20 PB49673382 72
3.13374675059
0.0918 0.3024 2.9808 0.1107 5.0000
BT-20 5-(4-fluorophenyl)-3-hydroxy-4-(5-methyl-2-furoyl)-1-(3-pyridinylmethyl)-1,5-dihydro-2H-pyrrol-2-one 72
inf
1.0460 0.0369 0.0000 0.9732 0.0100
BT-20 SB1-F-21 72
0.696988451088
-0.7116 0.7843 0.8263 -0.6712 5.0000
BT-20 SB1-F-22 72
inf
0.8486 -0.0325 0.0000 1.0000 0.0100
BT-20 SJB2-043 72
0.626589137637
-0.6216 0.5257 0.7914 -0.6048 3.3941
BT-20 SJB3-019A 72
0.340138717913
-0.6009 0.8217 0.3987 -0.6067 5.0000
BT-20 STK547622 72
inf
1.1526 -0.0532 0.0000 1.0000 0.0100
BT-20 Vialinin A 72
5.11668603811
-0.6101 0.3004 9.2727 -0.7177 1.4971
BT-20 Degrasyn 72
1.87496854329
-0.6371 0.6302 2.2190 -0.6608 5.0000
BT-20 Sepantronium 72
0.00899052444777
-0.5379 1.5452 0.0105 -0.5979 5.0000
BT-20 b-AP15 72
0.164472498608
-0.6967 1.0402 0.2405 -0.6510 2.1937
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