Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Primary Target | Pathway | Mean Normalized Growth Rate Inhibition Value | Increased Fraction Dead |
|---|---|---|---|---|---|---|
| Hs 578T | A-1210477 | 1.0 | Mcl-1 | Misc | 1.0188 | 0.00233 |
| MCF 10A | A-1210477 | 0.1 | Mcl-1 | Misc | 0.9996 | 0.00015 |
| Hs 578T | A-1210477 | 0.01 | Mcl-1 | Misc | 1.0025 | 0.00038 |
| Hs 578T | A-1210477 | 0.31623 | Mcl-1 | Misc | 1.0063 | -0.00376 |
| MCF 10A | A-1210477 | 0.001 | Mcl-1 | Misc | 0.9990 | -0.00061 |
| MCF 10A | A-1210477 | 0.031623 | Mcl-1 | Misc | 1.0045 | 0.00073 |
| Hs 578T | A-1210477 | 0.001 | Mcl-1 | Misc | 0.9753 | -0.00407 |
| Hs 578T | A-1210477 | 0.0031623 | Mcl-1 | Misc | 1.0209 | 0.00287 |
| Hs 578T | A-1210477 | 0.031623 | Mcl-1 | Misc | 0.9795 | -0.00203 |
| Hs 578T | A-1210477 | 0.1 | Mcl-1 | Misc | 1.0153 | -0.00231 |
| Hs 578T | A-1210477 | 3.1623 | Mcl-1 | Misc | 1.0615 | 0.00422 |
| Hs 578T | A-1210477 | 10.0 | Mcl-1 | Misc | 0.9419 | 0.00168 |
| MCF 10A | A-1210477 | 0.0031623 | Mcl-1 | Misc | 1.0050 | 0.00067 |
| MCF 10A | A-1210477 | 0.01 | Mcl-1 | Misc | 1.0049 | 0.00097 |
| HCC1806 | A-1210477 | 1.0 | Mcl-1 | Misc | 1.0685 | 0.00202 |
| HCC1806 | A-1210477 | 10.0 | Mcl-1 | Misc | 0.9047 | 0.02127 |
| HCC1806 | A-1210477 | 0.31623 | Mcl-1 | Misc | 1.0678 | -0.00565 |
| HCC1806 | A-1210477 | 0.031623 | Mcl-1 | Misc | 0.9977 | 0.00363 |
| HCC1806 | A-1210477 | 0.01 | Mcl-1 | Misc | 0.9898 | 0.00630 |
| HCC1806 | A-1210477 | 3.1623 | Mcl-1 | Misc | 1.0029 | -0.00692 |
| HCC1806 | A-1210477 | 0.0031623 | Mcl-1 | Misc | 1.0324 | -0.00234 |
| HCC1806 | A-1210477 | 0.001 | Mcl-1 | Misc | 0.9844 | -0.00747 |
| HCC1806 | A-1210477 | 0.1 | Mcl-1 | Misc | 0.9950 | 0.00255 |
| MCF 10A | A-1210477 | 1.0 | Mcl-1 | Misc | 1.0068 | -0.00085 |
| MCF 10A | A-1210477 | 0.31623 | Mcl-1 | Misc | 1.0036 | -0.00030 |