Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics. - Dataset (ID:20269)
Data Columns
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- 17 Data Columns
| Name | Description | Display Name | Data Type | Unit | Precision | Readout Type | Replicate | Comments |
|---|---|---|---|---|---|---|---|---|
| antibody | Antibody perturbagen | Antibody | antibody | |||||
| cell | Cell reagent | Cell | cell | |||||
| gRHillCoefficient | Maximal slope of the dose-response curve | GR Hill Coefficient | Numeric | 4 | ||||
| gRinf | Asymptotic value (concentration = infinity) for the sigmoidal curve fit to the dose-response data | GRinf | Numeric | 4 | ||||
| gRmax | Normalized growth inhibition rate at the highest tested perturbagen concentration | GRmax | Numeric | 4 | ||||
| nominalDivisionRate | Estimated number of divisions of the DMSO-treated control over the course of the assay | Nominal Division Rate | Numeric | 4 | ||||
| gRAOC | Integral of GR(c) over the range of concentrations tested | GR_AOC | Numeric | 4 | ||||
| smallMolecule | Small molecule perturbagen | Small Molecule | small_molecule | |||||
| concUnit | Concentration unit for GR50 and GEC50 | Conc Unit | Text | |||||
| biologicalReplicateID | Biological Replicate ID | Text | ||||||
| perturbagenClass | Perturbagen Class | Text | ||||||
| perturbagenTarget | Perturbagen Target | Text | ||||||
| gEC50 | Perturbagen concentration that results in 50% efficacy | GEC50 | Text | |||||
| transcriptionalSubtype | Transcriptional subtype of cell line | Transcriptional Subtype | Text | |||||
| clinicalSubtype | Clinical subtype of cell line | Clinical Subtype | Text | |||||
| gR50 | Perturbagen concentration at which GR(c)=0.5 | GR50 | Text | |||||
| gRR2 | r^2 for the sigmoidal curve fit to the dose-response data | GR r2 | Text |
- 17 Data Columns