Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
184A1
NM
Basal
(Z)-4-Hydroxytamoxifen
ESR1
0.000427
uM
9047.132
1.0270 1.0778 0.6985
184A1
NM
Basal
(Z)-4-Hydroxytamoxifen
ESR1
0.00213
uM
9047.132
0.9693 0.9128 0.6985
184A1
NM
Basal
(Z)-4-Hydroxytamoxifen
ESR1
0.0107
uM
9047.132
0.8736 0.6481 0.6985
184A1
NM
Basal
(Z)-4-Hydroxytamoxifen
ESR1
0.0533
uM
9047.132
0.9788 0.9394 0.6985
184A1
NM
Basal
(Z)-4-Hydroxytamoxifen
ESR1
0.267
uM
9047.132
0.9995 0.9985 0.6985
184A1
NM
Basal
(Z)-4-Hydroxytamoxifen
ESR1
1.33
uM
9047.132
0.9661 0.9036 0.6985
184A1
NM
Basal
(Z)-4-Hydroxytamoxifen
ESR1
6.67
uM
9047.132
0.8373 0.5511 0.6985
184A1
NM
Basal
(Z)-4-Hydroxytamoxifen
ESR1
33.3
uM
9047.132
0.7816 0.4055 0.6985
184A1
NM
Basal
(Z)-4-Hydroxytamoxifen
ESR1
167
uM
9047.132
0.9698 0.9141 0.6985
600MPE
HR+
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.000427
uM
7791.016
1.0572 1.1416 0.8138
600MPE
HR+
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.00213
uM
7791.016
1.0245 1.0604 0.8138
600MPE
HR+
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.0107
uM
7791.016
1.0744 1.1842 0.8138
600MPE
HR+
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.0533
uM
7791.016
1.0302 1.0745 0.8138
600MPE
HR+
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.267
uM
7791.016
1.0193 1.0476 0.8138
600MPE
HR+
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
1.33
uM
7791.016
1.0196 1.0483 0.8138
600MPE
HR+
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
6.67
uM
7791.016
1.0201 1.0496 0.8138
600MPE
HR+
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
33.3
uM
7791.016
0.7533 0.4121 0.8138
600MPE
HR+
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
167
uM
7791.016
0.6272 0.1274 0.8138
600MPE
HR+
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.000427
uM
9118.019
1.0600 1.1119 1.0707
600MPE
HR+
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.00213
uM
9118.019
1.0577 1.1076 1.0707
600MPE
HR+
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.0107
uM
9118.019
1.0672 1.1253 1.0707
600MPE
HR+
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.0533
uM
9118.019
1.0092 1.0172 1.0707
600MPE
HR+
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.267
uM
9118.019
1.0546 1.1018 1.0707
600MPE
HR+
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
1.33
uM
9118.019
1.0516 1.0961 1.0707
600MPE
HR+
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
6.67
uM
9118.019
0.9670 0.9382 1.0707
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