Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZR75B | HR+ | Luminal | ZM-447439 | AURK | AURK | 0.0064 | uM | 11939.16 | 0.9919 | 0.9903 | 1.6749 | |
| ZR75B | HR+ | Luminal | ZM-447439 | AURK | AURK | 0.032 | uM | 11939.16 | 0.9836 | 0.9804 | 1.6749 | |
| ZR75B | HR+ | Luminal | ZM-447439 | AURK | AURK | 0.16 | uM | 11939.16 | 1.0296 | 1.0352 | 1.6749 | |
| ZR75B | HR+ | Luminal | ZM-447439 | AURK | AURK | 0.8 | uM | 11939.16 | 0.6652 | 0.5680 | 1.6749 | |
| ZR75B | HR+ | Luminal | ZM-447439 | AURK | AURK | 4 | uM | 11939.16 | 0.8228 | 0.7801 | 1.6749 | |
| ZR75B | HR+ | Luminal | ZM-447439 | AURK | AURK | 20 | uM | 11939.16 | 0.5361 | 0.3784 | 1.6749 | |
| ZR75B | HR+ | Luminal | ZM-447439 | AURK | AURK | 100 | uM | 11939.16 | 0.6889 | 0.6011 | 1.6749 |