Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

Filter results: >>>>
Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
600MPE
HR+
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
33.3
uM
9118.019
0.9617 0.9284 1.0707
600MPE
HR+
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
167
uM
9118.019
0.1820 -0.5926 1.0707
AU565
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.000427
uM
7793.016
0.9621 0.9345 1.1616
AU565
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.00213
uM
7793.016
0.9450 0.9049 1.1616
AU565
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.0107
uM
7793.016
0.9778 0.9617 1.1616
AU565
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.0533
uM
7793.016
0.9595 0.9300 1.1616
AU565
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.267
uM
7793.016
0.9996 0.9993 1.1616
AU565
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
1.33
uM
7793.016
0.9314 0.8813 1.1616
AU565
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
6.67
uM
7793.016
0.8176 0.6816 1.1616
AU565
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
33.3
uM
7793.016
0.8354 0.7132 1.1616
AU565
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
167
uM
7793.016
0.0495 -0.8497 1.1616
AU565
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.000427
uM
7794.016
1.0541 1.0547 1.9541
AU565
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.00213
uM
7794.016
0.9024 0.8976 1.9541
AU565
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.0107
uM
7794.016
1.0422 1.0428 1.9541
AU565
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.0533
uM
7794.016
1.0010 1.0011 1.9541
AU565
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.267
uM
7794.016
1.0490 1.0496 1.9541
AU565
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
1.33
uM
7794.016
0.9399 0.9375 1.9541
AU565
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
6.67
uM
7794.016
0.8308 0.8190 1.9541
AU565
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
33.3
uM
7794.016
0.2935 0.0679 1.9541
AU565
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
167
uM
7794.016
0.7456 0.7210 1.9541
BT-474
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.000427
uM
7797.016
0.9719 0.8925 0.5155
BT-474
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.00213
uM
7797.016
0.9519 0.8176 0.5155
BT-474
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.0107
uM
7797.016
0.8963 0.6174 0.5155
BT-474
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.0533
uM
7797.016
0.8871 0.5852 0.5155
BT-474
HER2amp
Luminal
(Z)-4-Hydroxytamoxifen
ESR1
0.267
uM
7797.016
0.8639 0.5059 0.5155