Highly-multiplexed imaging by Cyclic Immunofluorescence (CycIF) of protein levels and protein phosphorylation states in the MCF 10A breast cell line treated with EGF or four kinase inhibitors - Dataset (ID:20267)

Proteins Studied

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  • 1 to 25 of 44 Proteins
LINCS ID Name HMS LINCS ID UniProt ID Alternative Names Provider Mutation Phosphlorylation State Domain Protein Description
200482 Akt-1 200482 P31749
RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha
200483 Akt-2 200483 P31751
RAC-beta serine/threonine-protein kinase; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-beta
200484 Akt-3 200484 Q9Y243
RAC-gamma serine/threonine-protein kinase; Protein kinase Akt-3; Protein kinase B gamma; PKB gamma; RAC-PK-gamma; STK-2
200507 EGFR 200507 P00533
Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
200537 mTOR 200537 P42345
Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; Mechanistic target of rapamycin; Rapamycin and FKBP12 target 1; Rapamycin target protein 1
200543 p53 200543 P04637
Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53
200598 VEGFR-2 200598 P35968
Vascular endothelial growth factor receptor 2; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; KDR; Protein-tyrosine kinase receptor flk-1; CD309; VEGFR2
201294 H3 (pS10) 201294 P68431 pS10
201295 p21 201295 P38936
Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6
201296 KI-67 201296 P46013
Antigen KI-67
201297 Rb (pS807; pS811) 201297 P06400 pS807; pS811
201298 S6 (pS235; pS236) 201298 P62753 pS235; pS236
201299 S6 (pS240; pS244) 201299 P62753 pS240; pS244
201302 PCNA 201302 P12004
Proliferating cell nuclear antigen; Cyclin
201303 ERK-1 (pT202; pY204) 201303 P27361 pT202; pY204
201304 ERK-2 (pT185; pY187) 201304 P28482 pT185; pY187
201305 K4 201305 P19013
Keratin, type II cytoskeletal 4; Cytokeratin-4; CK-4; Keratin-4; Type-II keratin Kb4
201306 K5 201306 P13647
Keratin, type II cytoskeletal 5; 58 kDa cytokeratin; Cytokeratin-5; CK-5; Keratin-5; Type-II keratin Kb5
201307 K6A 201307 P02538
Keratin, type II cytoskeletal 6A; Cytokeratin-6A; CK-6A; Cytokeratin-6D; CK-6D; Keratin-6A; Type-II keratin Kb6; Hom s 5
201308 K6B 201308 P04259
Keratin, type II cytoskeletal 6B; Cytokeratin-6B; CK-6B; Keratin-6B; Type-II keratin Kb10
201309 K6C 201309 P48668
Keratin, type II cytoskeletal 6C; Cytokeratin-6C; CK-6C; Cytokeratin-6E; CK-6E; Keratin K6h; Keratin-6C; Type-II keratin Kb12
201310 K8 201310 P05787
Keratin, type II cytoskeletal 8; Cytokeratin-8; CK-8; Type-II keratin Kb8
201311 K10 201311 P13645
Keratin, type I cytoskeletal 10; Cytokeratin-10; CK-10
201312 K13 201312 P13646
Keratin, type I cytoskeletal 13; Cytokeratin-13; CK-13
201313 K18 201313 P05783
Keratin, type I cytoskeletal 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18
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  • 1 to 25 of 44 Proteins