TKI-258 KINOMEscan - Dataset (ID:20168)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Protein | Kd | Conc unit |
|---|---|---|---|
| Dovitinib | AAK1 | 170.0 | nM |
| Dovitinib | ABL1(E255K)-phosphorylated | 75.0 | nM |
| Dovitinib | ABL1(F317I)-nonphosphorylated | nM | |
| Dovitinib | ABL1(F317I)-phosphorylated | 4500.0 | nM |
| Dovitinib | ABL1(F317L)-nonphosphorylated | 1500.0 | nM |
| Dovitinib | ABL1(F317L)-phosphorylated | 1100.0 | nM |
| Dovitinib | ABL1(H396P)-nonphosphorylated | 42.0 | nM |
| Dovitinib | ABL1(H396P)-phosphorylated | 60.0 | nM |
| Dovitinib | ABL1(M351T)-phosphorylated | 48.0 | nM |
| Dovitinib | ABL1(Q252H)-nonphosphorylated | 75.0 | nM |
| Dovitinib | ABL1(Q252H)-phosphorylated | 58.0 | nM |
| Dovitinib | ABL1(T315I)-nonphosphorylated | 110.0 | nM |
| Dovitinib | ABL1(T315I)-phosphorylated | 31.0 | nM |
| Dovitinib | ABL1(Y253F)-phosphorylated | 46.0 | nM |
| Dovitinib | ABL1-nonphosphorylated | 100.0 | nM |
| Dovitinib | ABL1-phosphorylated | 54.0 | nM |
| Dovitinib | ABL2 | nM | |
| Dovitinib | ACVR1 | nM | |
| Dovitinib | ACVR1B | nM | |
| Dovitinib | ACVR2A | nM | |
| Dovitinib | ACVR2B | nM | |
| Dovitinib | ACVRL1 | nM | |
| Dovitinib | ADCK3 | nM | |
| Dovitinib | ADCK4 | nM | |
| Dovitinib | AKT1 | nM |