Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| GSK461364 | MCF7 | -4.4776 | 0.8031 | -6.3506 | -4.6631 | -6.4936 | 3.1375 | 0.3164 | 0.3789 | 7.0589 |
| GSK461364 | SK-BR-3 | -4.4776 | 0.8909 | -7.6476 | -7.5380 | -7.6994 | 3.9790 | 0.3129 | 0.3129 | 5.8281 |
| GSK461364 | MDA-MB-231 | -4.4776 | 0.8566 | -7.8021 | -7.7101 | -7.7688 | 3.9985 | 0.2728 | 0.2728 | 5.0535 |
| GSK461364 | AU565 | -4.4776 | 0.9163 | -7.8996 | -7.8424 | -7.9567 | 3.9990 | 0.1548 | 0.1548 | 4.6399 |
| GSK461364 | BT-20 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| GSK461364 | BT-474 | -4.4776 | 0.7677 | -4.9305 | -4.9304 | -5.0842 | 3.9990 | 0.0000 | 0.0152 | 7.4055 |
| GSK461364 | BT-483 | -4.4776 | 0.8228 | -4.9223 | -4.9223 | -5.7449 | 2.2735 | 0.0000 | 0.0889 | 7.5231 |
| GSK461364 | BT-549 | -4.4776 | 0.9641 | -7.4546 | -7.3658 | -7.4956 | 1.5300 | 0.1350 | 0.1350 | 5.0110 |
| GSK461364 | CAMA-1 | -4.4776 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 7.0491 |
| GSK461364 | HCC1143 | -4.4776 | 0.8745 | -6.5206 | -6.4846 | -7.1518 | 2.1907 | 0.1222 | 0.2496 | 5.9762 |
| GSK461364 | HCC1395 | -4.4776 | 0.9094 | -8.1721 | -8.0244 | -8.5680 | 2.3616 | 0.2050 | 0.2074 | 4.4694 |
| GSK461364 | HCC1419 | -4.4776 | 0.8303 | -4.9400 | -4.8793 | -5.1187 | 3.9990 | 0.2136 | 0.2246 | 8.3641 |
| GSK461364 | HCC1428 | -4.4776 | 0.9592 | -4.9400 | -4.9399 | -5.2690 | 3.3400 | 0.0000 | 0.0203 | 7.7381 |
| GSK461364 | HCC1569 | -4.4776 | 0.7965 | -5.0714 | -5.0714 | -5.7745 | 0.3696 | 0.0000 | 0.3763 | 6.5207 |
| GSK461364 | HCC1806 | -4.4776 | 0.9549 | -7.9236 | -7.8853 | -7.9576 | 4.0000 | 0.1486 | 0.1486 | 4.4396 |
| GSK461364 | HCC1937 | -4.4776 | 0.9499 | -6.4746 | -6.3569 | -7.4841 | 0.4122 | 0.0508 | 0.1980 | 5.7820 |
| GSK461364 | HCC1954 | -4.4776 | 0.9031 | -8.6121 | -8.5601 | -8.6498 | 3.7270 | 0.1966 | 0.1966 | 3.8376 |
| GSK461364 | HCC202 | -4.4776 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 6.6220 |
| GSK461364 | HCC38 | -4.4776 | 0.9483 | -7.5136 | -7.4139 | -7.5675 | 3.7870 | 0.2893 | 0.2893 | 5.5548 |
| GSK461364 | HCC70 | -4.4776 | 0.8008 | -7.0721 | -5.1370 | -7.5055 | 2.2167 | 0.2518 | 0.3533 | 6.3285 |
| GSK461364 | Hs 578T | -4.4776 | 0.9074 | -7.7706 | -7.6340 | -7.8504 | 2.5630 | 0.2968 | 0.2968 | 5.2331 |
| GSK461364 | MB 157 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| GSK461364 | MDA-MB-134-VI | -4.4776 | 0.7987 | -4.7865 | -4.6231 | -4.9107 | 3.9995 | 0.0159 | 0.2089 | 7.6944 |
| GSK461364 | MDA-MB-157 | -4.4776 | 0.9444 | -9.0436 | -8.9391 | -9.0610 | 2.6360 | 0.2340 | 0.2340 | 3.5893 |
| GSK461364 | MDA-MB-175-VII | -4.4776 | 0.7103 | -4.6478 | -4.6477 | -4.9999 | 1.7670 | 0.0000 | 0.3335 | 7.1799 |