EFM-192C - Cell Line (ID:51116)

HMS LINCS ID: 51116
Name: EFM-192C
Alternative Names:
LINCS ID:
Alternative ID: CLO_0002891
Parent Cell Line:
Reference Source: Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures ACC 311
Organism: Homo sapiens
Organ: breast
Tissue:
Cell Type: epithelioid
Details of Cell Type:
Donor Sex: female
Donor Age: 46
Donor Ethnicity: Caucasian
Donor Health Status:
Disease: DOID:3458, breast adenocarcinoma
Details of Disease: breast adenocarcinoma
Production Details: From DSMZ: established from the pleural effusion of the left side (14 days after EFM-192A) of a 46-year-old Caucasian woman with breast adenocarcinoma
Genetic Modification(s): none
Known Mutations: ERBB2 amplification
Citation Information for Mutations: Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures ACC 311
Verification Reference Profile:
Growth Properties: adherent; From DSMZ: epitheloid adherent cells growing as monolayers
Recommended Culture Conditions: From DSMZ: Medium: 80% RPMI 1640 + 20% h.i. FBS. Subculture: Optimal split ratio is 1:2 to 1:3 once a week using trypsin/EDTA. Seed out at ca. 5-8 x 104 cells/cm2 or 2 x 106 cells/25 cm2 flask. Incubation: at 37°C with 5% CO2. Doubling time: ca. 4 days.
Relevant Citations:
Usage Note:
Comments:
Date Publicly Available: 2016-08-24
Most Recent Update: 2017-05-02

Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20268
Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates.
Analysis
20269
Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics.
Analysis

Batch Information:

HMS LINCS Batch ID Provider Provider Catalog ID Provider Batch ID
51116-1 Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures ACC 311