MDA-MB-436 - Cell Line (ID:50333)
|HMS LINCS ID:||50333|
|Parent Cell Line:|
|Reference Source:||ATCC HTB-130|
|Details of Cell Type:|
|Donor Health Status:|
|Details of Disease:||breast adenocarcinoma|
|Citation Information for Mutations:||COSS1240172|
|Verification Reference Profile:|
|Recommended Culture Conditions:||From MGH/CMT as specified by cell provider: Leibovitz's L-15 medium with 10 mcg/ml insulin, 16 mcg/ml glutathione, 90%; fetal bovine serum, 10%. Subculturing: Subcultures are prepared by scraping. Remove spent medium, add 3 to 5 ml of fresh medium, dislodge cells from the floor of the flask, aspirate and dispense into new flasks. Subculture every 6 to 8 days. Subcultivation ratio: A subcultivation ratio of 1:2 is recommended|
|Date Publicly Available:||2012-07-31|
|Most Recent Update:||2016-04-04|
|HMS Dataset ID||Dataset Title||HMS Dataset Type|
Metrics other than potency reveal systematic variation in responses to cancer drugs
Basal profile of receptor tyrosine kinase signaling network measured by ELISA
Cell signaling response to growth factors measured by high throughput microscopy
Cell signaling response to growth factors measured by ELISA
Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates.
Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics.
Breast Cancer Profiling Project, Drug Sensitivity 1: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens. Dataset 1 of 2: Normalized growth rate inhibition values.
Breast Cancer Profiling Project, Drug Sensitivity 1: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens. Dataset 2 of 2: Calculated dose response metrics.
Breast Cancer Profiling Project, Gene Expression 1: Baseline mRNA sequencing on 35 breast cell lines
Breast Cancer Profiling Project – Proteomics 1: 1 total proteome dataset for a 35-cell line breast cancer panel under basal conditions
Breast Cancer Profiling Project – Proteomics 2: 1 phosphoproteome dataset (including phosphotyrosine enrichment) for a 35-cell line breast cancer panel under basal conditions
|HMS LINCS Batch ID||Provider||Provider Catalog ID||Provider Batch ID|