ERK-1 (pT202; pY204); ERK-1 (pT202); ERK-2 (pT185; pY187); ERK-2 (pT185) - Antibody (ID:80063)
| HMS LINCS ID: | 80063 |
| Name: | ERK-1 (pT202; pY204); ERK-1 (pT202); ERK-2 (pT185; pY187); ERK-2 (pT185) |
| Alternative Names: | Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP® Rabbit mAb #4370 |
| Clone Name: | D13.14.4E |
| Resource Identification Initiative ID: | AB_2297462 |
| LINCS ID: | |
| Type: | natural |
| Nominal Protein Target(s): | ERK-1 (pT202; pY204) |
| Nominal Protein Target HMS LINCS ID(s): | 201303 |
| Nominal Non-protein Target: | |
| Organism of Nominal Target: | Homo sapiens |
| Other Target Information: | Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP® Rabbit mAb detects endogenous levels of p44 and p42 MAP Kinase (Erk1 and Erk2) when dually phosphorylated at Thr202 and Tyr204 of Erk1 (Thr185 and Tyr187 of Erk2), and singly phosphorylated at Thr202. This antibody does not cross-react with the corresponding phosphorylated residues of either JNK/SAPK or p38 MAP kinases. Species Reactivity: Human, Mouse, Rat, Hamster, Monkey, Mink, D. melanogaster, Zebrafish, Bovine, Dog, Pig, S. cerevisiae. Species predicted to react based on 100% sequence homology: Chicken, C. elegans. (source: Cell Signaling Technology) |
| Other Human Protein Target HMS LINCS ID(s): | 201304; 201337; 201338 |
| Immunogen: | Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Thr202/Tyr204 of human p44 MAP kinase. (source: Cell Signaling Technology) |
| Immunogen Sequence: | |
| Fc Domain Source Species: | rabbit |
| Clonality: | monoclonal |
| Fc Domain Isotype: | IgG |
| Source Organism for Production: | rabbit |
| Production Details: | |
| Conjugate or Label: | |
| Labeling Details: | |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | 2016-09-14 |
| Most Recent Update: | 2016-12-22 |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20265 | Multiplexed imaging of protein levels and protein phosphorylation states in the MCF 10A breast cell line treated with EGF | Microscopy/Imaging |
| 20266 | Multiplexed imaging of protein levels and protein phosphorylation states in the MCF 10A breast cell line treated with nine kinase inhibitors | Microscopy/Imaging |
| 20275 | Phosphorylation state and protein levels measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (immunofluorescence dataset 2 of 4) | Microscopy/Imaging |
| 20277 | Phosphorylation state and protein levels measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with combinations of two compounds (immunofluorescence dataset 4 of 4) | Microscopy/Imaging |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Catalog ID | Provider Batch ID |
|---|---|---|---|
| 80063-1 | Cell Signaling Technology | 4370L | |
| 80063-2 | Cell Signaling Technology | 4370 |